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Jacqueline Kennedy, she was known for her style and for overseeing the restoration of the White House.

Laura Bush, known for her advocacy for education, women's health, and human rights.

Imelda Marcos, known for her collection of shoes, she was also involved in social and cultural projects.

Eva Perón, she was noted for her efforts to help the poor and for her role in getting women's suffrage.

Yvonne de Gaulle, she was known for her devout Catholicism and work with charities.

Jehan Sadat, she played a key role in reforming Egypt’s civil rights laws and promoted volunteerism.

Michelle Obama, known for her advocacy on poverty awareness, education, nutrition, physical activity, and healthy eating.

Indira Gandhi, though not a First Lady, she was the first and, to date, the only female Prime Minister of India.

Benazir Bhutto, though not a First Lady, she was the first woman to head a democratic government in a majority Muslim nation.

Nancy Reagan, known for her 'Just Say No' drug awareness campaign.

Betty Ford, known for her candid approach to her fight against breast cancer and substance abuse, founding the Betty Ford Center.

Eleanor Roosevelt, she transformed the role of the First Lady by her active participation in American politics.

Hillary Rodham Clinton, known for her work on healthcare reform and as an advocate for gender equality and health care.

Clementine Churchill, she helped with her husband’s morale during World War II and worked for charitable organizations.

Pat Nixon, she is remembered for her volunteerism and her involvement in various social projects around the world.

Corazon Aquino, though not a First Lady, she was the first female president in Philippines after the end of Marcos regime.

Lady Bird Johnson, she actively promoted beautification of America's cities and highways, known as the 'Head Start' program.

Rosalynn Carter, known for her advocacy on mental health, she worked to improve community-based mental health programs.

Barbara Bush, known for her dedication to literacy as a foundation of family and community, and for her work with various charities.