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Last active ruler of the Ptolemaic Kingdom of Egypt, engaged in diplomatic relations with Rome.

Played a key role in the lifting of the Siege of Orléans during the Hundred Years' War, which led to the coronation of Charles VII of France.

The Virgin Queen who established Protestantism in England and defeated the Spanish Armada in 1588.

Russian empress who expanded Russian territories and sought to modernize its culture on Western European lines.

Pioneering figure in the women's suffrage movement in the United States.

Helped women win the right to vote in the United Kingdom, founder of the Women's Social and Political Union (WSPU).

Fourth Prime Minister of Israel, one of the first women to hold such an office in the world.

First and only female Prime Minister of India, led during a time of great change and conflict.

First female Prime Minister of the United Kingdom, known for her uncompromising politics and leadership style.

First woman to head a democratic government in a majority Muslim nation (Pakistan).

First female Chancellor of Germany, notable for her handling of the Eurozone crisis and her open-door policy to refugees.

First elected female head of state in Africa as president of Liberia.

First female President of Chile, served two non-consecutive terms, appointed as the UN High Commissioner for Human Rights.

Youngest female head of government when elected Prime Minister of New Zealand, her leadership during crises gained international praise.

First female Vice President of the United States, as well as the highest-ranking female official in U.S. history.

First woman in the world to be elected as prime minister (Sri Lanka).

First female President of the Philippines and the first woman to hold that office in Asia, restored democracy after the long dictatorship of Ferdinand Marcos.

First woman to become Prime Minister of Denmark, CEO of Save the Children International.

First female President of Iceland and the world's first democratically elected female head of state.

First female United States Secretary of State, played a key role in the NATO bombing campaign against Yugoslavia.

First African American woman to serve as the United States Secretary of State, important figure in the Bush administration's response to 9/11.

Advocate for democracy and human rights in Myanmar, she spent many years under house arrest.

First female President of Finland, known for her promotion of human rights and social justice.

First female President of the Philippines to serve two terms and the first to ascend to the presidency via succession.