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Behavioral Genetics Terminology
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Heritability
A statistic that indicates what proportion of the variation in a trait within a population can be attributed to genetic differences. It informs us about the potential genetic influence on behaviors and psychological traits.
Genotype
The genetic makeup of an organism, representing the set of genes it carries. Genotypes can influence observable characteristics and behaviors.
Phenotype
The set of observable characteristics of an individual resulting from the interaction of its genotype with the environment. This includes physical traits as well as behaviors.
Polygenic Inheritance
A process where multiple genes contribute to the phenotype of a trait. It's relevant in behaviors and complex traits which are influenced by multiple genetic factors.
Epistasis
A phenomenon where the effects of one gene are modified by one or several other genes, which can influence the expression of genetic traits and behaviors.
Behavioral Phenotyping
The process of assessing the behavioral traits of an organism, often used to understand the genetic basis of behaviors in animal models.
Quantitative Trait Locus (QTL)
A region of DNA that is associated with a particular phenotypic trait, which can be measured on a quantitative scale, like height or intelligence.
Candidate Gene Approach
A method in genetics in which researchers start with an educated guess about which gene might influence a trait or behavior, often based on the gene's function or position in the genome.
Genome-Wide Association Studies (GWAS)
Research approach that involves rapidly scanning markers across complete sets of DNA of many people to find genetic variations associated with a particular disease or trait.
Twin Studies
A research design used to estimate the genetic and environmental influences on phenotypes by comparing the similarities between monozygotic (identical) and dizygotic (fraternal) twins.
Adoption Studies
Studies in which the adopted individual's traits and behaviors are compared to those of their biological and adoptive families to discern genetic influences from environmental factors.
Molecular Genetics
The field of biology that studies the structure and function of genes at a molecular level and how genetic variations affect biological processes and behaviors.
Allele
One of the variant forms of a gene at a particular locus, or position, on a chromosome. Different alleles can produce variation in inherited characteristics and behaviors.
Linkage Disequilibrium
The non-random association of alleles at different loci, which can indicate that the loci are physically near each other on the chromosome and may be inherited together.
Pleiotropy
A condition when one gene influences two or more seemingly unrelated phenotypic traits, which can complicate the understanding of genotype-phenotype relationships.
Single Nucleotide Polymorphism (SNP)
A variation in a single base pair in the DNA sequence among individuals. SNPs can contribute to the variability of a trait or susceptibility to diseases.
Endophenotype
A measurable component that is unseen by the unaided eye, along the pathway between the gene and disease, it helps to identify genetic determinants of complex behaviors or diseases.
Copy Number Variation (CNV)
A phenomenon in which sections of the genome are repeated and the number of repeats can vary between individuals in the population. CNVs can influence gene expression and phenotypic traits.
Gene-Environment Interaction
The situation in which environmental factors affect individuals differently, depending on their genetic makeup. This interaction is key to understanding the full range of behaviors and psychological traits.
Genomic Imprinting
An epigenetic phenomenon by which certain genes can be expressed in a parent-of-origin-specific manner. It's an exception to the usual rule of genes being expressed from both inherited copies.
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