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Behavioral Genetics Terminology

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Heritability

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A statistic that indicates what proportion of the variation in a trait within a population can be attributed to genetic differences. It informs us about the potential genetic influence on behaviors and psychological traits.

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Genotype

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The genetic makeup of an organism, representing the set of genes it carries. Genotypes can influence observable characteristics and behaviors.

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Phenotype

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The set of observable characteristics of an individual resulting from the interaction of its genotype with the environment. This includes physical traits as well as behaviors.

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Polygenic Inheritance

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A process where multiple genes contribute to the phenotype of a trait. It's relevant in behaviors and complex traits which are influenced by multiple genetic factors.

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Epistasis

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A phenomenon where the effects of one gene are modified by one or several other genes, which can influence the expression of genetic traits and behaviors.

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Behavioral Phenotyping

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The process of assessing the behavioral traits of an organism, often used to understand the genetic basis of behaviors in animal models.

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Quantitative Trait Locus (QTL)

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A region of DNA that is associated with a particular phenotypic trait, which can be measured on a quantitative scale, like height or intelligence.

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Candidate Gene Approach

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A method in genetics in which researchers start with an educated guess about which gene might influence a trait or behavior, often based on the gene's function or position in the genome.

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Genome-Wide Association Studies (GWAS)

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Research approach that involves rapidly scanning markers across complete sets of DNA of many people to find genetic variations associated with a particular disease or trait.

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Twin Studies

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A research design used to estimate the genetic and environmental influences on phenotypes by comparing the similarities between monozygotic (identical) and dizygotic (fraternal) twins.

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Adoption Studies

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Studies in which the adopted individual's traits and behaviors are compared to those of their biological and adoptive families to discern genetic influences from environmental factors.

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Molecular Genetics

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The field of biology that studies the structure and function of genes at a molecular level and how genetic variations affect biological processes and behaviors.

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Allele

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One of the variant forms of a gene at a particular locus, or position, on a chromosome. Different alleles can produce variation in inherited characteristics and behaviors.

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Linkage Disequilibrium

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The non-random association of alleles at different loci, which can indicate that the loci are physically near each other on the chromosome and may be inherited together.

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Pleiotropy

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A condition when one gene influences two or more seemingly unrelated phenotypic traits, which can complicate the understanding of genotype-phenotype relationships.

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Single Nucleotide Polymorphism (SNP)

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A variation in a single base pair in the DNA sequence among individuals. SNPs can contribute to the variability of a trait or susceptibility to diseases.

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Endophenotype

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A measurable component that is unseen by the unaided eye, along the pathway between the gene and disease, it helps to identify genetic determinants of complex behaviors or diseases.

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Copy Number Variation (CNV)

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A phenomenon in which sections of the genome are repeated and the number of repeats can vary between individuals in the population. CNVs can influence gene expression and phenotypic traits.

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Gene-Environment Interaction

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The situation in which environmental factors affect individuals differently, depending on their genetic makeup. This interaction is key to understanding the full range of behaviors and psychological traits.

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Genomic Imprinting

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An epigenetic phenomenon by which certain genes can be expressed in a parent-of-origin-specific manner. It's an exception to the usual rule of genes being expressed from both inherited copies.

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