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Artist: Leonardo da Vinci, Year: c. 1503–1506, Influence: Set a precedent for portrait painting and became one of the most famous paintings in the world.

Artist: Leonardo da Vinci, Year: 1495–1498, Influence: Revolutionized the depiction of biblical scenes by capturing a crucial moment and imbuing it with high emotional tension.

Artist: Raphael, Year: 1511, Influence: Exemplified the ideals of the Renaissance with its portrayal of classical philosophers, influencing centuries of art and thought.

Artist: Sandro Botticelli, Year: c. 1484–1486, Influence: Captivated audiences with its portrayal of classical mythology and helped define the standards of beauty in Western art.

Artist: Michelangelo, Year: 1508–1512, Influence: It redefined the capabilities of fresco technique and had a profound impact on Western art.

Artist: Michelangelo, Year: 1501–1504, Influence: Became an icon of Renaissance art and a symbol of Florence and humanist ideals.

Artist: Jan van Eyck, Year: 1434, Influence: Laid the foundation for the Northern Renaissance and contributed to the development of portraiture with its attention to detail.

Artist: Michelangelo, Year: 1511, Influence: Influenced the representation of the human body in art and theology.

Artist: Sandro Botticelli, Year: c. 1482, Influence: Blended themes of classical mythology with complex composition to influence the High Renaissance and Mannerist artists.

Artist: Giorgione, Year: c. 1508, Influence: Sparked new approaches to landscape painting and the enigmatic themes influenced the Venetian school.

Artist: Leonardo da Vinci, Year: c. 1490, Influence: Became an iconic representation of the blend between art and science during the Renaissance, influencing both disciplines.

Artist: Paolo Uccello, Year: c. 1438–1440, Influence: It marked a transitional period toward the use of perspective, impacting later Renaissance artists.

Artist: Gentile da Fabriano, Year: 1423, Influence: It contributed to the development of the International Gothic style and influenced Renaissance depictions of this biblical scene.

Artist: Piero della Francesca, Year: c. 1472, Influence: It influenced portrait painting by combining realism with idealization.

Artist: Leonardo da Vinci, Year: c. 1472–1475, Influence: Influenced religious art by showing a natural and serene interaction between figures in a domestic setting.

Artist: Michelangelo, Year: c. 1506–1507, Influence: Influenced the use of circular frames (tondo) and depicted a complex interplay of figures that inspired Mannerism.

Artist: Raphael, Year: 1505, Influence: Exemplified ideals of beauty and harmony which influenced religious and secular painting styles.

Artist: Andrea del Verrocchio and Leonardo da Vinci, Year: 1472–1475, Influence: Showcased the merging of styles between teacher and student, influencing the transition towards High Renaissance.

Artist: Andrea Mantegna, Year: c. 1501, Influence: Utilized foreshortening to create a powerful illusion of depth, influencing later depictions of dramatic subjects.

Artist: Masaccio, Year: 1425, Influence: Introduced a more naturalistic and emotional style to frescoes, which influenced the development of Renaissance art.

Artist: Jan van Eyck, Year: 1433, Influence: Often considered as one of the earliest examples of realistic portraiture in Western art.

Artist: Raphael, Year: 1504, Influence: Demonstrated mastery of perspective and composition, setting the stage for later Renaissance artworks.

Artist: Giotto, Year: c. 1305, Influence: Marked a pivotal point in the transition from Byzantine to more naturalistic styles in the art of storytelling.

Artist: Paolo Uccello, Year: c. 1470, Influence: Highlighted the application of perspective and the depiction of movement, influencing later Renaissance painters.

Artist: Pieter Bruegel the Elder, Year: 1563, Influence: It introduced Northern Renaissance artists to the power of landscape and the detailed depiction of human folly.

Artist: Hans Holbein the Younger, Year: 1533, Influence: Demonstrated the use of symbolism and the skill of anamorphic perspective, impacting portrait and trompe-l'oeil art.

Artist: Hubert and Jan van Eyck, Year: Completed 1432, Influence: It was pivotal in establishing oil painting as the dominant medium in Northern Europe and influenced the use of realism.

Artist: Pieter Bruegel the Elder, Year: 1565, Influence: The work is notable for its early portrayal of secular life and its detailed representation of seasonal changes, affecting the themes and methods of future painters.

Artist: Giorgione, Year: c. 1500, Influence: Advanced the genre of pastorals and infused landscape art with atmospheric effects that influenced later Venetian painters.

Artist: Titian, Year: 1538, Influence: Set new standards for the depiction of the female nude, influencing artists for centuries with its sensual and intimate portrayal.

Artist: Paolo Veronese, Year: c. 1570s, Influence: The series' use of complex iconography and opulent style influenced the course of Venetian painting and decorative narrative cycles.

Artist: Giotto, Year: c. 1304–1306, Influence: Revolutionized narrative painting by introducing spatial consistency and emotional expressiveness.