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Endocrine Disorders

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Hyperprolactinemia

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Affected Hormones: Prolactin Symptoms: Galactorrhea, Amenorrhea, Infertility

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Adrenogenital Syndrome (AGS)

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Affected Hormones: Cortisol, Aldosterone, Androgens Symptoms: Virilization or feminization, Electrolyte imbalance, Precocious puberty

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Hypoparathyroidism

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Affected Hormones: Parathyroid Hormone (PTH) Symptoms: Numbness, Trousseau's sign, Chvostek's sign

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Type 2 Diabetes Mellitus

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Affected Hormones: Insulin Symptoms: Polyuria, Polydipsia, Fatigue

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Type 1 Diabetes Mellitus

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Affected Hormones: Insulin Symptoms: Polyuria, Polydipsia, Weight loss

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Hyperthyroidism

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Affected Hormones: Thyroid Hormones (T3 & T4) Symptoms: Nervousness, Tachycardia, Weight loss

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Multiple Endocrine Neoplasia (MEN)

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Affected Hormones: Parathyroid Hormone, Gastrin, Insulin, and others Symptoms: Vary based on tumors present

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Zollinger-Ellison Syndrome (ZES)

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Affected Hormones: Gastrin Symptoms: Peptic ulcers, Abdominal pain, Diarrhea

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Hypothyroidism

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Affected Hormones: Thyroid Hormones (T3 & T4) Symptoms: Lethargy, Bradycardia, Weight gain

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Hyperparathyroidism

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Affected Hormones: Parathyroid Hormone (PTH) Symptoms: Bone pain, Kidney stones, Hypercalcemia

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Congenital Adrenal Hyperplasia (CAH)

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Affected Hormones: Cortisol, Aldosterone, Androgens Symptoms: Ambiguous genitalia (in females), Salt-wasting, Precocious puberty

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Diabetes Insipidus

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Affected Hormones: Antidiuretic Hormone (ADH) Symptoms: Excessive urination, Thirst, Dehydration

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Osteoporosis

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Affected Hormones: Estrogen, Testosterone, Parathyroid Hormone (PTH) Symptoms: Fractures, Loss of height, Bone pain

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Insulinoma

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Affected Hormones: Insulin Symptoms: Hypoglycemia, Confusion, Seizures

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Acromegaly

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Affected Hormones: Growth Hormone (GH) Symptoms: Enlarged hands/feet, Prominent jaw, Coarse facial features

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Cushing's Disease

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Affected Hormones: Cortisol Symptoms: Moon face, Buffalo hump, Abdominal striae

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Addison's Disease

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Affected Hormones: Cortisol, Aldosterone Symptoms: Fatigue, Hyperpigmentation, Hypotension

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Hypogonadism

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Affected Hormones: Testosterone, Estrogen Symptoms: Decreased libido, Infertility, Osteoporosis

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Goiter

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Affected Hormones: Thyroid Hormones (T3 & T4) Symptoms: Neck swelling, Dysphagia, Cough

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Empty Sella Syndrome

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Affected Hormones: Multiple pituitary hormones Symptoms: Fatigue, Headache, Visual disturbances

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Graves' Disease

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Affected Hormones: Thyroid Hormones (T3 & T4) Symptoms: Exophthalmos, Heat intolerance, Weight loss

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Polycystic Ovary Syndrome (PCOS)

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Affected Hormones: Androgens, Insulin Symptoms: Hirsutism, Irregular Menstrual Cycles, Infertility

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Pheochromocytoma

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Affected Hormones: Catecholamines (Epinephrine & Norepinephrine) Symptoms: Hypertension, Palpitations, Diaphoresis

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Sheehan's Syndrome

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Affected Hormones: Multiple pituitary hormones Symptoms: Postpartum lactation failure, Fatigue, Hypotension

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Hypopituitarism

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Affected Hormones: Multiple pituitary hormones Symptoms: Fatigue, Decreased libido, Hypothyroidism

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Carcinoid Syndrome

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Affected Hormones: Serotonin, Histamine Symptoms: Flushing, Diarrhea, Wheezing

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Hashimoto's Thyroiditis

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Affected Hormones: Thyroid Hormones (T3 & T4) Symptoms: Fatigue, Weight gain, Cold intolerance

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Cushing's Syndrome

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Affected Hormones: Cortisol Symptoms: Central obesity, Striae, Hypertension

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Gigantism

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Affected Hormones: Growth Hormone (GH) Symptoms: Rapid growth, Increased height, Delayed puberty

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