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Oncology Terminology

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Malignant

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A term for diseases in which abnormal cells divide without control and can invade nearby tissues or spread to other parts of the body.

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Cancer Screening

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Tests and procedures used to detect cancer at an early stage before symptoms appear in hopes of increasing chances for successful treatment.

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Pathology

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The scientific study of disease and is instrumental in diagnosis, monitoring progression, and assessing treatment efficacy in cancer.

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Radiosensitivity

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The susceptibility of cancer cells, tissues, or tumors to radiation, used to predict the effectiveness of radiation therapy.

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Biomarker

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A biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease, such as cancer.

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Chemotherapy

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A type of cancer treatment that uses drugs to destroy cancer cells by stopping them from growing and dividing.

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Oncogene

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A gene that in certain circumstances can transform a cell into a tumor cell.

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Tumor

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An abnormal mass of tissue that may be benign or malignant and can grow in any part of the body.

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Cancer Staging

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The process of determining the extent to which a cancer has developed by spreading.

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Cytology

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The study of cells, including their function, structure, and life cycle, frequently used in cancer diagnostics to examine cell samples for abnormalities.

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Radiotherapy

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Another term for radiation therapy, which uses ionizing radiation to kill cancer cells and shrink tumors.

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Carcinoma

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A type of cancer that starts in cells that make up the skin or the tissue lining organs, such as the liver or kidneys.

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Oncologist

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A doctor who specializes in treating cancer and provides medical care for a person diagnosed with cancer.

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Hyperplasia

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An increase in the number of cells in a tissue or organ, which can sometimes precede cancer development.

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Benign

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Refers to a condition, tumor, or growth that is not cancerous and does not spread to other parts of the body.

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Neoadjuvant Therapy

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Treatment given prior to the main treatment, such as chemotherapy or radiation given before surgery to shrink a tumor.

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Tumor Marker

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Substances, often proteins, that are produced by cancer cells or by the body in response to cancer, which can be used to help diagnose and manage cancer.

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Oncology

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The branch of medicine that specializes in the diagnosis and treatment of cancer.

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Biopsy

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A medical test involving the removal of cells or tissues for examination to determine the presence or extent of disease.

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Sarcoma

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A type of cancer that begins in bone or in the soft tissues of the body, including muscle, fat, blood vessels, lymph vessels, and fibrous tissue.

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Radiation Therapy

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A treatment that uses high-energy radiation to shrink tumors and kill cancer cells.

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Cytotoxic

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Refers to agents or processes that are toxic to cells, such as chemotherapy drugs which can kill or damage cells.

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Targeted Therapy

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A type of cancer treatment that targets the changes in cancer cells that help them grow, divide, and spread.

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Oncotherapy

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Any therapy used in the treatment of cancer, which can include surgery, chemotherapy, radiation therapy, and more.

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Oncogenic

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Having the potential to cause cancer.

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Dysplasia

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The presence of abnormal cells within a tissue or organ, which may signify a precancerous state.

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Tumor Suppressor Gene

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A gene that protects a cell from one step on the path to cancer, and when this is mutated, it can lead to cancer.

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Angiogenesis

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The process through which new blood vessels form, which can allow tumors to grow and metastasize by supplying nutrients and oxygen.

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Carcinogenesis

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The process by which normal cells are transformed into cancer cells.

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Immunotherapy

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A type of cancer treatment that helps your immune system fight cancer.

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Proto-oncogene

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A normal gene that can become an oncogene due to mutations or increased expression, potentially leading to cancer.

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Adjuvant Therapy

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Additional cancer treatment given after the primary treatment to lower the risk that the cancer will come back.

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Leukemia

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A type of cancer that affects the blood and bone marrow, characterized by an overproduction of white blood cells.

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Hormone Therapy

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A treatment method that decreases the production of hormones or blocks their action to stop or slow down the growth of cancer cells.

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Remission

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A period in which the signs and symptoms of cancer are reduced or disappear; it can be partial or complete.

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Palliative Care

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Specialized medical care for people with serious illnesses like cancer, focusing on providing relief from the symptoms and stress of the illness.

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Neoplasm

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Another term for a tumor, indicating an abnormal growth of tissue.

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Apoptosis

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A process of programmed cell death which, when disrupted, may lead to cancer.

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Hematology

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The branch of medicine concerned with the study and treatment of blood diseases, including various forms of leukemia and lymphoma.

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Melanoma

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A type of cancer that usually begins in the melanocytes, the cells that produce the pigment melanin which colors the skin, eyes, and hair.

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Oncolytic Virus

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A virus that infects and breaks down cancer cells without causing disease in healthy cells.

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Cancer Survivorship

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The phase of cancer care that focuses on the health and life of a person with cancer post-treatment, including physical, psychological, and social issues.

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Anaplasia

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A lack of differentiation of cells often characteristic of aggressive cancerous tumors.

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Karnofsky Performance Status

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A scale that measures the ability of cancer patients to perform ordinary tasks, with higher scores indicating greater ability to carry out daily activities.

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Lymphoma

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A type of cancer that originates in the lymphatic system, which is part of the immune system and includes the lymph nodes, spleen, thymus gland, and bone marrow.

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Metastasis

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The spread of cancer cells from the place where they first formed to another part of the body.

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Carcinogen

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Any substance that can cause or contribute to the formation of cancer.

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Radioresistance

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The resistance that cancer cells or tumors exhibit to radiation therapy, often necessitating higher doses or different treatment methods.

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Oncolytic Therapy

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A treatment that uses oncolytic viruses to infect and destroy cancer cells.

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