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Historical Pandemics and Diseases
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Black Death
Time Period: 1347-1351, Death Toll: 75-200 million, Areas Affected: Europe, Asia, Africa
Spanish Flu
Time Period: 1918-1919, Death Toll: 40-50 million, Areas Affected: Worldwide
Smallpox
Time Period: Various outbreaks, Death Toll: Estimated 300 million in the 20th century, Areas Affected: Worldwide
HIV/AIDS
Time Period: Identified in 1981, ongoing, Death Toll: Over 36 million, Areas Affected: Worldwide
The Antonine Plague
Time Period: 165-180 AD, Death Toll: 5 million, Areas Affected: Roman Empire
The Justinian Plague
Time Period: 541-542 AD, Death Toll: 25-50 million, Areas Affected: Byzantine Empire and neighboring territories
The Third Cholera Pandemic
Time Period: 1852-1860, Death Toll: 1 million, Areas Affected: Asia, Europe, North America, Africa
The Asian Flu
Time Period: 1957-1958, Death Toll: 1-2 million, Areas Affected: Asia, Worldwide
The Hong Kong Flu
Time Period: 1968-1969, Death Toll: 1 million, Areas Affected: Hong Kong, Worldwide
The Plague of Athens
Time Period: 430-426 BC, Death Toll: Estimated 75,000-100,000, Areas Affected: Athens, Ancient Greece
The Great Plague of London
Time Period: 1665-1666, Death Toll: Estimated 100,000, Areas Affected: London, England
COVID-19
Time Period: 2019-present, Death Toll: Over 6.3 million (as of knowledge cutoff in 2023), Areas Affected: Worldwide
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