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Genetics and Heredity

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What is a gene?

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A gene is a unit of heredity that is transferred from a parent to offspring and is held to determine some characteristic of the offspring.

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What is a genetic marker?

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A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species.

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What is a single nucleotide polymorphism (SNP)?

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A SNP is a variation at a single position in a DNA sequence among individuals, which can affect how humans develop diseases and respond to pathogens, chemicals, drugs, and vaccines.

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What is genomics?

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Genomics is the study of genomes, the complete set of DNA within a single cell of an organism, and focuses on the structure, function, evolution, and mapping of genomes.

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What is epigenetics?

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Epigenetics is the study of changes in gene function that do not involve changes in the DNA sequence and are heritable through cell division.

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What is natural selection?

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Natural selection is the process whereby organisms better adapted to their environment tend to survive and produce more offspring.

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What is an exon?

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An exon is a portion of a gene that codes for amino acids and is expressed in the final mRNA that is translated into protein.

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What is a genetic disease?

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A genetic disease is a disease caused by abnormalities in an individual's genome, with the abnormality ranging from a small mutation to major chromosomal changes.

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What is a genome?

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A genome is the complete set of genes or genetic material present in a cell or organism.

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What is linkage disequilibrium?

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Linkage disequilibrium occurs when alleles at two linked loci are non-randomly associated with each other within a population.

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What is a vector in genetic engineering?

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In genetic engineering, a vector is a vehicle used to transfer genetic material to a target cell, such as a plasmid or a viral vector.

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What is heritability?

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Heritability is the proportion of observed variation in a particular trait that can be attributed to inherited genetic factors in contrast to environmental ones.

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What is a genotype?

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A genotype is the genetic constitution of an individual organism.

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What is a mutation?

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A mutation is a change in the DNA sequence that can affect genes and may lead to heritable changes in an organism's characteristics.

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What is genetic recombination?

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Genetic recombination is the process by which two DNA molecule exchange genetic information, resulting in the production of new combinations of alleles.

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What is codominance?

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Codominance occurs when both alleles in a gene pair in a heterozygote are fully expressed, with neither one being recessive or masking the other.

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What is incomplete dominance?

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Incomplete dominance is a genetic situation in which one allele does not completely dominate another allele, resulting in a new phenotype.

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What is a phenotype?

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A phenotype is the set of observable characteristics of an individual resulting from the interaction of its genotype with the environment.

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What is a karyotype?

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A karyotype is the number and visual appearance of the chromosomes in the cell nuclei of an organism or species.

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What is a nucleotide?

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A nucleotide is the basic building block of nucleic acids (DNA and RNA), composed of a sugar, a phosphate, and a nitrogenous base.

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What is gene expression?

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Gene expression is the process by which the instructions in a gene are used to synthesize gene products, which are often proteins.

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What is a transgenic organism?

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A transgenic organism is an organism that has been genetically modified to contain genetic material from another species.

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What is an intron?

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An intron is a non-coding section of a gene that is transcribed into RNA but is removed before translation into protein.

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What are somatic cells?

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Somatic cells are any cells in the body that are not reproductive cells, with each containing the full set of chromosomes typical for the species.

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What is an allele?

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An allele is one of two or more versions of a gene that are found at the same place on a chromosome.

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What is genetic drift?

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Genetic drift is the change in the frequency of an existing gene variant (allele) in a population due to random sampling of organisms.

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What is the Hardy-Weinberg principle?

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The Hardy-Weinberg principle states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences.

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What is CRISPR-Cas9?

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CRISPR-Cas9 is a genome editing system that allows for precise, directed changes to genomic DNA using an RNA-guided DNA endonuclease enzyme Cas9.

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What is alternative splicing?

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Alternative splicing is a regulated process during gene expression that results in a single gene coding for multiple proteins.

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What is meiosis?

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Meiosis is a type of cell division that reduces the chromosome number by half, creating four haploid cells, each genetically distinct from the parent cell that gave rise to them.

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What are autosomes?

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Autosomes are chromosomes that are not sex chromosomes; they are present in the same number and form in both males and females.

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What is Mendelian inheritance?

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Mendelian inheritance is the pattern of inheritance that follows the laws proposed by Gregor Mendel, involving dominance and segregation of genes.

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What is mitosis?

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Mitosis is a process where a single cell divides into two identical daughter cells (cell division).

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What is genetic engineering?

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Genetic engineering is the direct manipulation of an organism's genes using biotechnology, including editing, deletion, and insertion of new DNA.

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What is a sex chromosome?

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Sex chromosomes are the chromosomes that determine the sex of an individual, with humans typically having one pair (XX for females, XY for males).

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What is a chromosome?

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A chromosome is a long DNA molecule with part or all of the genetic material of an organism.

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What are gametes?

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Gametes are reproductive cells (sperm and eggs) that carry half the genetic information of an individual, one set of chromosomes, and are haploid.

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What is a polygenic trait?

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A polygenic trait is a trait that is controlled by more than one gene, often resulting in a continuous distribution of phenotypes.

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What is a locus?

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A locus is the specific physical location of a gene or other significant sequence on a chromosome.

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What is a plasmid?

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A plasmid is a small DNA molecule within a cell that is physically separated from chromosomal DNA and can replicate independently.

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