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Eleanor played a pivotal role in the politics of the 12th century, leading a Crusade, and acting as regent. She was a patron of the arts and participated in the establishment of medieval courtly culture.

Hildegard of Bingen contributed to medicine, music, and spiritual writings; her works include 'Scivias'. She is also known for her visionary theology and being a pioneer in the field of science and healing.

Joan of Arc was a French heroine who, driven by visions, played a key role in lifting the Siege of Orléans and turning the tide of the Hundred Years’ War. She was canonized as a saint by the Roman Catholic Church.

Christine de Pizan was one of the first women to make a living as a writer. She challenged the traditional misogynistic views of her time with her book 'The Book of the City of Ladies'.

Matilda was a supporter of Pope Gregory VII during the Investiture Controversy and was vital in the conflict against the Holy Roman Emperor. Her military and political influence was significant during the 11th century.

Theodora helped to expand the rights of women in the Byzantine Empire and was a co-ruler with her husband, Emperor Justinian I; she was influential in the passing of laws and administrative reforms.

Eleanor was the first wife of King Edward I and has been recognized for her cultural and diplomatic contributions. She accompanied Edward on the Ninth Crusade and was a patron of literature and architecture.

Margery Kempe is known for dictating 'The Book of Margery Kempe', considered by some as the first autobiography in the English language. She is noted for her pilgrimages to holy sites and her mystical experiences.

Catherine of Siena was a lay member of the Dominican Order, and she played a significant role in returning the Papacy from Avignon to Rome. She is recognized as a Doctor of the Church for her theological writings.