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Suggests that aging is caused by the accumulation of damage done by free radicals, which are unstable molecules that can cause cellular damage.

Proposes that aging is the result of accumulated damage to cells and tissues over time, much like how machines wear out.

States that aging is related to the shortening of telomeres at the ends of chromosomes, which limits the number of times a cell can divide.

Based on the observation that cells can only divide a certain number of times, which is referred to as the Hayflick Limit, after which they enter senescence and stop dividing.

Suggests that aging results from changes in the brain and endocrine glands, which are crucial for growth, metabolism, and response to stress.

Refers to the gradual deterioration of the immune system as part of the aging process, leading to increased vulnerability to infections and diseases.

Holds that aging is due to the cross-linking of proteins or other macromolecules, which results in decreased cell elasticity and impaired function.

Posits that lowering caloric intake can extend lifespan by reducing metabolic rate and oxidative damage to cells.

The theory that aging is the result of a decline in mitochondrial function, leading to a decrease in cellular energy production and increased oxidative damage.