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Stress and the Brain

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Altered brain function due to stress hormones

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The release of cortisol can inhibit the functioning of the prefrontal cortex, affecting decision making and emotional regulation.

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Chronic stress and hippocampal damage

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Long-term stress can lead to the degeneration of the hippocampus, impairing learning and memory.

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Stress and synaptic plasticity

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Excessive stress can affect synaptic plasticity, potentially causing a reduction in cognitive flexibility.

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Impact of stress on Neurotransmitter systems

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Stress can disrupt the balance of neurotransmitters like serotonin and dopamine, leading to mood disorders.

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Stress-induced neuroinflammation

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Stress can trigger neuroinflammatory pathways that may contribute to the development of neurodegenerative diseases.

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The role of stress in triggering the fight or flight response

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Acute stress activates the amygdala, leading to the release of adrenaline and noradrenaline, which prepare the body for a fight or flight response.

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Stress and the alteration of gene expression

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Stress can lead to epigenetic changes, altering the expression of genes related to brain function and mental health.

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Effect of chronic stress on brain aging

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Chronic stress has been associated with accelerated aging in the brain, potentially leading to early cognitive decline.

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Stress and the risk of psychiatric disorders

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Stress is a significant risk factor for the onset of various psychiatric disorders, including PTSD, depression, and anxiety disorders.

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Stress and brain metabolism

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Stress can affect brain metabolism, impacting the use of glucose and leading to energy imbalances in the brain.

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