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Hematopoiesis Process
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Natural Killer (NK) Cell
A lymphocyte involved in the innate immune response against tumor and virally infected cells; comes from common lymphoid progenitor.
Granulocyte
A type of white blood cell filled with microscopic granules; includes neutrophils, eosinophils, and basophils.
Common Lymphoid Progenitor (CLP)
A derivative of HSCs that will give rise to lymphoid lineage: B cells, T cells, and natural killer cells.
Proerythroblast
An early stage in erythrocyte development; will mature into erythroblasts.
Dendritic Cell
A type of antigen-presenting cell that processes and presents antigens to T cells; derived from monocytes.
Erythrocyte
A mature red blood cell responsible for oxygen transport, derived from erythroblasts.
T Lymphocyte (T cell)
A type of lymphocyte involved in cell-mediated immunity; also derived from the common lymphoid progenitor.
Eosinophil
A granulocyte involved in combating parasitic infections and in allergic reactions.
Basophil
The least common type of granulocyte; participates in allergic responses and releases histamine.
Band Cell
An immature neutrophil with a non-segmented nucleus that will mature into a segmented neutrophil.
Plasma Cell
A mature B cell that produces and secretes large quantities of antibodies; derived from plasmablasts.
Common Myeloid Progenitor (CMP)
A cell type derived from HSCs that will give rise to myeloid lineage: erythrocytes, megakaryocytes, monocytes, and granulocytes.
Erythroblast
An immature red blood cell (erythrocyte) that is found in bone marrow and will eventually lose its nucleus to become a mature erythrocyte.
Megakaryocyte-erythroid Progenitor (MEP)
A progenitor cell derived from CMP that will give rise to megakaryocytes and erythrocytes.
Neutrophil
The most common type of granulocyte, crucial for fighting bacterial infections.
Progranulocyte
An intermediate cell stage that precedes the formation of specific types of granulocytes.
Megakaryocyte
A large bone marrow cell responsible for the production of thrombocytes (platelets), involved in clotting.
Pluripotent Hematopoietic Stem Cell (PHSC)
The precursor to HSC, capable of giving rise to multiple cell types, including those outside of hematopoiesis.
Myelocyte
A stage in the development of granulocytes and monocytes from myeloblasts.
Hematopoietic Stem Cell (HSC)
The multipotent stem cell that gives rise to all blood cells; resides in bone marrow.
Myeloblast
An immature precursor of granulocytes, found in bone marrow.
Megakaryoblast
The precursor cell to a megakaryocyte, involved in the production of blood thrombocytes.
Monocyte
A type of white blood cell that will leave the bone marrow to become a macrophage or dendritic cell in peripheral tissues.
B Lymphocyte (B cell)
A type of lymphocyte responsible for producing antibodies; derived from the common lymphoid progenitor.
Plasmablast
A precursor to plasma cell, which is an activated B cell that secretes antibodies.
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