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Hematopoiesis Process
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Eosinophil
A granulocyte involved in combating parasitic infections and in allergic reactions.
Proerythroblast
An early stage in erythrocyte development; will mature into erythroblasts.
Monocyte
A type of white blood cell that will leave the bone marrow to become a macrophage or dendritic cell in peripheral tissues.
Natural Killer (NK) Cell
A lymphocyte involved in the innate immune response against tumor and virally infected cells; comes from common lymphoid progenitor.
Granulocyte
A type of white blood cell filled with microscopic granules; includes neutrophils, eosinophils, and basophils.
Megakaryocyte-erythroid Progenitor (MEP)
A progenitor cell derived from CMP that will give rise to megakaryocytes and erythrocytes.
Band Cell
An immature neutrophil with a non-segmented nucleus that will mature into a segmented neutrophil.
Dendritic Cell
A type of antigen-presenting cell that processes and presents antigens to T cells; derived from monocytes.
Basophil
The least common type of granulocyte; participates in allergic responses and releases histamine.
Erythroblast
An immature red blood cell (erythrocyte) that is found in bone marrow and will eventually lose its nucleus to become a mature erythrocyte.
Erythrocyte
A mature red blood cell responsible for oxygen transport, derived from erythroblasts.
Neutrophil
The most common type of granulocyte, crucial for fighting bacterial infections.
Megakaryoblast
The precursor cell to a megakaryocyte, involved in the production of blood thrombocytes.
Megakaryocyte
A large bone marrow cell responsible for the production of thrombocytes (platelets), involved in clotting.
T Lymphocyte (T cell)
A type of lymphocyte involved in cell-mediated immunity; also derived from the common lymphoid progenitor.
Myelocyte
A stage in the development of granulocytes and monocytes from myeloblasts.
Common Lymphoid Progenitor (CLP)
A derivative of HSCs that will give rise to lymphoid lineage: B cells, T cells, and natural killer cells.
Common Myeloid Progenitor (CMP)
A cell type derived from HSCs that will give rise to myeloid lineage: erythrocytes, megakaryocytes, monocytes, and granulocytes.
Progranulocyte
An intermediate cell stage that precedes the formation of specific types of granulocytes.
Hematopoietic Stem Cell (HSC)
The multipotent stem cell that gives rise to all blood cells; resides in bone marrow.
Pluripotent Hematopoietic Stem Cell (PHSC)
The precursor to HSC, capable of giving rise to multiple cell types, including those outside of hematopoiesis.
Plasmablast
A precursor to plasma cell, which is an activated B cell that secretes antibodies.
Myeloblast
An immature precursor of granulocytes, found in bone marrow.
B Lymphocyte (B cell)
A type of lymphocyte responsible for producing antibodies; derived from the common lymphoid progenitor.
Plasma Cell
A mature B cell that produces and secretes large quantities of antibodies; derived from plasmablasts.
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