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Tobacco Use Disorder, treatments include nicotine replacement therapy (NRT), bupropion, and varenicline.

Alcohol Use Disorder (AUD), treatments include behavioral therapies, medications like Naltrexone, and support groups like AA.

Opioid Use Disorder, treatments include medications like methadone, buprenorphine, and naltrexone, in addition to counseling and behavioral therapies.

Cannabis Use Disorder, treatments are primarily behavioral therapies as there are no FDA-approved medications specifically for cannabis use disorder.

Inhalant Use Disorder, treatments include supportive care, behavioral counseling, and addressing any co-occurring mental health conditions.

Cocaine Use Disorder, no medications are currently approved to treat cocaine addiction, but behavioral therapies like CBT are commonly used.

Anabolic-Androgenic Steroid Use Disorder, treatment may include hormonal therapy, behavioral therapy, and support groups.

Methamphetamine Use Disorder, treatments often involve behavioral therapies such as cognitive-behavioral therapy and contingency management interventions.

Hallucinogen Use Disorder, primarily treated with psychosocial support and behavioral therapies, as there are no specific pharmacological treatments.

MDMA Use Disorder, treatment typically involves cognitive behavioral therapy, supportive care, and harm reduction strategies.

Benzodiazepine Use Disorder, treatment includes gradual tapering of the drug, cognitive-behavioral therapy, and sometimes medications like flumazenil.

Phencyclidine Use Disorder, treatment involves behavioral therapies, general supportive care, and sometimes antipsychotic medication for severe cases.

Synthetic Cannabinoid Use Disorder, treatment is mostly supportive with behavioral interventions like psychoeducation and cognitive-behavioral therapy.

Ketamine Use Disorder, treatment involves behavioral therapies and supportive care as well as monitoring for urinary and psychological issues.

Sedative Use Disorder, treatment typically involves a slow taper off the medication, cognitive-behavioral therapy, and treating any co-occurring disorders.

Stimulant Use Disorder, treatments include behavioral therapies, tapering of the medication dose, and sometimes off-label use of other medications to treat symptoms.

Barbiturate Use Disorder, treatment often requires a medical detox due to the risk of severe withdrawal symptoms, alongside therapy and support programs.

Mescaline Use Disorder, treatment consists of psychosocial support, behavioral counseling, and dealing with any co-occurring mental health issues.

GHB Use Disorder, treatment primarily consists of medically-supervised detoxification and behavioral therapies.

Synthetic Cathinone Use Disorder, no specific treatment; management includes supportive care, behavioral therapies, and sometimes antipsychotic medications.

Dextromethorphan Use Disorder, treated with behavioral therapy and supportive care, often involving education about risks and withdrawal management.

Salvia Use Disorder, treatment is largely supportive and educational, focusing on psychosocial interventions and therapy.

Khat Use Disorder, treatment is mainly psychosocial, with counseling and support as key components due to the lack of pharmacotherapy options.

Nitrous Oxide Use Disorder, treatment includes education on risks, support groups, and in some cases, psychological or psychiatric help.