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Basic Genetics Vocabulary

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DNA

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Deoxyribonucleic Acid, the molecule that carries genetic instructions for the development, functioning, and reproduction of all known living organisms.

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Gene

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A segment of DNA that is responsible for the physical and inheritable characteristics or phenotype of an organism.

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Mitosis

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A type of cell division that results in two daughter cells each having the same number and kind of chromosomes as the parent nucleus.

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mRNA

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Messenger RNA, a type of RNA that carries genetic information from the DNA to the ribosome, where it specifies the amino acid sequence.

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Allele

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One of two or more alternative forms of a gene that are found at the same place on a chromosome.

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Mutation

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A change in the DNA sequence that can lead to a change in the gene product.

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tRNA

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Transfer RNA, a type of RNA that carries amino acids to the ribosome for incorporation into a protein.

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Epigenetics

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The study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself.

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DNA Replication

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The process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules.

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rRNA

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Ribosomal RNA, a molecular component of a ribosome, the cell's essential protein factory.

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Linkage

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The tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction.

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Genetic Drift

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A mechanism of evolution in which allele frequencies of a population change over generations due to chance (sampling error).

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Transcription

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The process in which a segment of DNA is copied into RNA by the enzyme RNA polymerase.

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Meiosis

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A type of cell division that reduces the chromosome number by half, resulting in the production of haploid gametes or spores.

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Punnett Square

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A diagram used to predict the outcome of a particular cross or breeding experiment.

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Recessive

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An allele that only expresses its phenotypic effect when homozygous; its effect is masked by a dominant allele.

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Codon

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A sequence of three nucleotides that together form a unit of genetic code in a DNA or RNA molecule.

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Polygenic Inheritance

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A non-Mendelian form of inheritance in which a trait is controlled by several genes at different loci.

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Karyotype

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The number, size, and shape of chromosomes in an organism.

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RNA

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Ribonucleic Acid, a molecule involved in protein synthesis and the transmission of genetic information.

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Translation

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The process in which ribosomes in a cell's cytoplasm create proteins, following transcription of DNA to RNA in the cell nucleus.

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Genetic Code

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The set of rules by which information encoded in genetic material (DNA or RNA sequences) is translated into proteins.

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Chromosome

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A long DNA molecule with part or all of the genetic material of an organism. Humans have 23 pairs.

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Genotype

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The genetic makeup of an organism; the combination of alleles for a given gene.

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Phenotype

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The physical appearance or biochemical characteristic of an organism as a result of the interaction of its genotype and the environment.

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Heterozygous

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Having two different alleles for a particular gene.

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Nucleotide

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The basic building block of DNA and RNA, consisting of a base, a molecule of sugar, and one phosphate group.

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Central Dogma

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The theory that genetic information flows from DNA to RNA to Protein, but not in reverse.

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Dominant

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An allele that expresses its phenotypic effect even when heterozygous with a recessive allele; if present, it determines the phenotype.

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Homozygous

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Having two identical alleles for a particular gene.

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