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DNA Structure and Function

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DNA Replication

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The process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules.

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RNA Primer

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A short strand of RNA that is synthesized by primase during DNA replication and provides a starting point for DNA polymerase.

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Histones

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Protein molecules around which DNA is tightly coiled in chromatin.

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Base Pair

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Two nitrogenous bases on opposite DNA strands that interact through hydrogen bonds; adenine pairs with thymine, and cytosine pairs with guanine.

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Chromatin

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The complex of DNA and protein found in the nucleus of eukaryotic cells, which when condensed forms chromosomes.

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Antiparallel Strands

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Refers to the opposite orientation of the two strands of DNA; one strand runs in the 5' to 3' direction and the other in the 3' to 5' direction.

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DNA Ligase

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An enzyme that joins the sugar-phosphate backbones of the Okazaki fragments to form a single, continuous DNA strand.

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DNA Polymerase

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An enzyme that synthesizes DNA molecules from deoxyribonucleotides, the building blocks of DNA.

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Nucleotide

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The basic building block of DNA, composed of a phosphate group, a sugar, and a nitrogenous base.

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Leading Strand

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The strand of the DNA double helix that is synthesized continuously during DNA replication.

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Double Helix

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The three-dimensional structure of DNA, consisting of two strands that twist around each other.

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Hydrogen Bond

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A weak bond between two molecules resulting from an electrostatic attraction between a proton in one molecule and an electronegative atom in the other.

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Deoxyribose Sugar

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A five-carbon sugar molecule that is part of the backbone of DNA molecules.

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Lagging Strand

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The strand of the DNA double helix that is synthesized discontinuously (in short segments) during DNA replication.

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Okazaki Fragments

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Short, newly synthesized DNA fragments that are formed on the lagging template strand during DNA replication.

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Complementary Base Pairing

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The specific pairing of base A with T and base C with G in DNA.

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Helicase

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An enzyme that is responsible for unwinding the DNA double helix during DNA replication.

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Genome

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The complete set of genes or genetic material present in a cell or organism.

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Phosphate Group

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A group of molecules that connects two deoxyribose sugars through phosphodiester bonds, forming the backbone of the DNA molecule.

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Nitrogenous Base

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A molecule found in DNA and RNA that encodes genetic information in cells.

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