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NRT provides a controlled dose of nicotine to ease withdrawal symptoms while quitting smoking. It's available in several forms like patches, gum, lozenges, inhalers, and nasal sprays. Effectiveness varies but combining NRT with behavior support can increase chances of quitting.

Hypnotherapy aims to change the smoker's mindset about smoking through suggestion while in a state of relaxation. Effectiveness is uncertain but some individuals may find it helpful when combined with other methods.

E-cigarettes allow users to inhale nicotine without most of the harmful effects of smoking. Their role in cessation is still being studied, but they may help by mimicking the behavioral aspects of smoking. Effectiveness as a cessation aid is debated.

Acupuncture involves inserting needles into specific points on the body. It's thought to stimulate the release of endorphins (natural pain relievers) that may help ease tobacco cravings. Effectiveness is inconclusive and may work for some individuals.

Varenicline works by partially activating nicotine receptors in the brain, reducing cravings and easing withdrawal symptoms. Its effectiveness can be higher than other medications and may triple the chances of quitting compared to placebo.

In counseling, individuals receive support and advice from health professionals to develop skills to quit smoking. Behavioral therapies can help change smoking habits. Effectiveness increases with the intensity and duration of the counseling.

Nicotine vaccines are an experimental treatment that stimulates the immune system to produce antibodies against nicotine, preventing it from entering the brain and causing pleasurable effects. Effectiveness is still under investigation and not yet available commercially.