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Drug-Laboratory Test Interactions

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Amiodarone

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Liver function tests (LFTs), Thyroid function tests (TFTs)

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Valproic Acid

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Valproic acid levels, Liver function tests (LFTs), Complete blood count (CBC)

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Phenobarbital

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Phenobarbital levels, Liver function tests (LFTs)

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Theophylline

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Theophylline levels, Liver function tests (LFTs)

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Lithium

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Lithium levels, Thyroid function tests

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Phenytoin

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Phenytoin levels, Albumin

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Cyclosporine

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Cyclosporine levels, Creatinine

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Insulin

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Blood glucose levels, Hemoglobin A1c (HbA1c)

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Carbamazepine

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Carbamazepine levels, Sodium levels

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Statins

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Liver function tests (LFTs), Creatine kinase (CK)

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Aspirin

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Bleeding time, Uric acid

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ACE Inhibitors

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Potassium levels, Creatinine

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Warfarin

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Prothrombin Time (PT) / International Normalized Ratio (INR)

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Digoxin

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Digoxin levels, Potassium levels

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Metformin

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Lactic acid, Kidney function tests

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Ethanol

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Blood alcohol concentration (BAC), Glucose levels

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Isoniazid (INH)

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Liver function tests (LFTs), Vitamin B6 levels

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Allopurinol

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Uric acid levels, Liver function tests (LFTs)

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Rifampin

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Liver function tests (LFTs), Complete blood count (CBC)

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Methotrexate

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Complete blood count (CBC), Liver function tests (LFTs), Creatinine

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Clozapine

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Clozapine levels, Complete blood count (CBC)

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Spironolactone

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Potassium levels, Renin and aldosterone

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Tacrolimus

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Tacrolimus levels, Creatinine

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Heparin

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Activated partial thromboplastin time (aPTT)

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Cholestyramine

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Vitamin K, A, D, E levels

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