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Serotonin Syndrome: High-risk Medications
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Fluoxetine
High
Sertraline
High
Citalopram
High
MDMA (Ecstasy)
Very High
Tramadol
Moderate to High
Linezolid
Moderate
Dextromethorphan
Moderate
Mirtazapine
Low to Moderate
LSD
Moderate
Methadone
Moderate
Venlafaxine
High
MAOIs (e.g., Phenelzine)
Very High
SSRIs + MAOIs
Very High
St. John's Wort
Moderate
Chlorpheniramine
Low
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