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Medications for Asthma & COPD
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Mepolizumab
Drug Class: Monoclonal Antibody Mechanism: Binds to IL-5, reducing the production and survival of eosinophils, which are implicated in certain types of asthma
Budesonide
Drug Class: Inhaled Corticosteroid Mechanism: Prevents the release of substances in the body that cause inflammation
Prednisone
Drug Class: Oral Corticosteroid Mechanism: Suppresses inflammation and the normal immune response
Aclidinium
Drug Class: Long-acting Muscarinic Antagonist Mechanism: Causes bronchodilation by blocking muscarinic receptors in airway smooth muscles
Ciclesonide
Drug Class: Inhaled Corticosteroid Mechanism: Prodrug that is activated in the lungs to a metabolite with anti-inflammatory activity
Albuterol
Drug Class: Short-acting Beta-2 Agonist Mechanism: Stimulates beta-2 receptors resulting in smooth muscle relaxation in the airways
Formoterol
Drug Class: Long-acting Beta-2 Agonist Mechanism: Activates beta-2 receptors causing bronchial smooth muscle relaxation
Montelukast
Drug Class: Leukotriene Receptor Antagonist Mechanism: Blocks leukotriene receptors to reduce airway edema, smooth muscle contraction, and inflammation
Fluticasone
Drug Class: Inhaled Corticosteroid Mechanism: Reduces inflammation and immune response in the airways
Beclomethasone
Drug Class: Inhaled Corticosteroid Mechanism: Anti-inflammatory properties reduce bronchial hyperresponsiveness
Zileuton
Drug Class: Leukotriene Synthesis Inhibitor Mechanism: Blocks 5-lipoxygenase enzyme necessary for the formation of leukotrienes
Berotralstat
Drug Class: Plasma Kallikrein Inhibitor Mechanism: Inhibits plasma kallikrein and prevents bradykinin production, decreasing inflammation and capillary leakage
Mometasone
Drug Class: Inhaled Corticosteroid Mechanism: Anti-inflammatory effect by decreasing the production of inflammatory mediators
Salmeterol
Drug Class: Long-acting Beta-2 Agonist Mechanism: Binds selectively to beta-2 receptors leading to bronchial smooth muscle relaxation
Ipratropium
Drug Class: Short-acting Muscarinic Antagonist Mechanism: Inhibits acetylcholine on bronchial smooth muscle, leading to bronchodilation
Omalizumab
Drug Class: Monoclonal Antibody Mechanism: Binds to IgE antibodies, preventing them from attaching to allergens and triggering the allergic response
Tiotropium
Drug Class: Long-acting Muscarinic Antagonist Mechanism: Blocks acetylcholine-induced bronchoconstriction by antagonizing muscarinic receptors
Indacaterol
Drug Class: Ultra-long-acting Beta-2 Agonist Mechanism: Provides bronchodilation by beta-2 receptor activation over 24 hours
Theophylline
Drug Class: Methylxanthine Mechanism: Nonselective phosphodiesterase inhibitor, increasing cAMP and leading to bronchodilation
Roflumilast
Drug Class: Phosphodiesterase-4 Inhibitor Mechanism: Reduces inflammation by inhibiting PDE4, increasing cAMP levels
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