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Veterinary Endocrinology

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Pheochromocytoma

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Symptoms: High blood pressure, rapid heart rate, panting. Diagnosis: Measurement of catecholamine levels, imaging studies. Treatment: Surgical removal of the tumor, medical management of blood pressure.

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Cushing's Disease (Hyperadrenocorticism)

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Symptoms: Increased appetite, thirst, and urination; pot-bellied appearance. Diagnosis: Low-dose dexamethasone suppression test or ACTH stimulation test. Treatment: Medications or surgery to remove adrenal tumor.

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Addison's Disease (Hypoadrenocorticism)

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Symptoms: Lethargy, vomiting, diarrhea, low blood pressure. Diagnosis: ACTH stimulation test. Treatment: Hormone replacement therapy with glucocorticoids and mineralocorticoids.

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Hypothyroidism

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Symptoms: Lethargy, weight gain, and skin problems. Diagnosis: Blood tests measuring T4 levels. Treatment: Thyroid hormone replacement therapy.

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Hyperthyroidism

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Symptoms: Weight loss, increased appetite, and hyperactivity. Diagnosis: Elevated T4 levels in blood tests. Treatment: Medications, radioactive iodine therapy, or surgery.

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Acromegaly

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Symptoms: Enlargement of the paws, face, and organs; diabetes symptoms. Diagnosis: Elevated growth hormone levels, imaging studies. Treatment: Surgery, radiation therapy, medical management.

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Diabetes Mellitus

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Symptoms: Excessive thirst, hunger, and urination; weight loss. Diagnosis: Elevated fasting blood glucose and urine glucose. Treatment: Insulin therapy, diet modification.

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Insulinoma

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Symptoms: Weakness, seizures, collapse. Diagnosis: Low fasting blood glucose, high insulin levels. Treatment: Surgical removal of the tumor, management of hypoglycemia.

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Primary Hypoparathyroidism

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Symptoms: Muscle tremors, seizures, stiff gait. Diagnosis: Low blood calcium, high phosphorus levels, low parathyroid hormone. Treatment: Calcium and vitamin D supplementation.

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Pituitary Dwarfism

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Symptoms: Stunted growth, retention of puppy coat, infertility. Diagnosis: Low growth hormone levels, genetic testing in some breeds. Treatment: Hormone replacement therapy, supportive care.

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Hypoglycemia

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Symptoms: Weakness, tremors, seizures. Diagnosis: Low blood sugar measurements. Treatment: Glucose supplementation orally or intravenously, addressing underlying cause.

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Thyroid Carcinoma

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Symptoms: Neck mass, hoarseness, difficulty breathing or swallowing. Diagnosis: Biopsy, imaging techniques. Treatment: Surgical removal, I-131 therapy, radiation therapy.

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Calcium Homeostasis Disorders (e.g., Milk Fever in cows)

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Symptoms: Muscle weakness, low body temperature, recumbency. Diagnosis: Low serum calcium levels. Treatment: Intravenous calcium solutions.

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Thyroid Neoplasia

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Symptoms: Palpable neck mass, sometimes coughing or changed bark. Diagnosis: Fine needle aspiration, imaging, hormone levels assessment. Treatment: Surgery, possible I-131 therapy or chemotherapy.

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Diabetic Ketoacidosis

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Symptoms: Vomiting, dehydration, lethargy. Diagnosis: High blood glucose levels, ketonuria. Treatment: Insulin therapy, fluid and electrolyte replacement.

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Estrous Cycle Disorders

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Symptoms: Irregular heat cycles, infertility. Diagnosis: Hormone measurements, reproductive tract examination. Treatment: Depends on cause; can include hormone therapy or surgery.

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Hyperaldosteronism

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Symptoms: Increased thirst and urination, weakness, hypertension. Diagnosis: Elevated aldosterone levels, blood chemistry, imaging. Treatment: Surgery for adrenal tumors, aldosterone antagonists, supportive care.

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Feline Hyperesthesia Syndrome

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Symptoms: Skin twitching, vocalizations, erratic behavior. Diagnosis: Rule out endocrine and other disorders, behavioral assessment. Treatment: Anti-convulsants, environmental modifications.

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Ovarian Remnant Syndrome

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Symptoms: Signs of estrus post-spaying, possible vaginal discharge. Diagnosis: Hormone assays indicating active ovarian tissue, exploratory surgery. Treatment: Surgical removal of leftover ovarian tissue.

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Secondary Hypoparathyroidism (Nutritional)

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Symptoms: Similar to primary hypoparathyroidism. Diagnosis: Blood tests show imbalances in calcium, phosphorus, and Vitamin D. Treatment: Dietary management and calcium supplementation.

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Testicular Tumors

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Symptoms: Swollen testicle(s), feminization, infertility. Diagnosis: Physical examination, ultrasound, hormonal assays. Treatment: Orchiectomy, chemotherapy for metastatic disease.

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Hyperparathyroidism

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Symptoms: Increased thirst and urination, softening of bones, kidney stones. Diagnosis: High blood calcium, elevated PTH. Treatment: Surgical removal of affected parathyroid glands, dietary management.

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Polycystic Ovary Syndrome (PCOS)

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Symptoms: Infrequent or prolonged estrous cycles, obesity, sometimes excessive hair growth. Diagnosis: Ultrasound of ovaries, hormone level assessments. Treatment: Weight management, possibly ovarian drilling or hormone therapy.

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Congenital Hypothyroidism

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Symptoms: Dwarfism, mental dullness, thickened facial features. Diagnosis: Low thyroid hormone levels at a young age. Treatment: Lifelong thyroid hormone replacement.

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Adrenal Sex Hormone Imbalance

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Symptoms: Hair loss, swollen vulva or prepuce, secondary urinary tract infections. Diagnosis: Hormone assays, imaging studies. Treatment: Medication to control hormone production, surgery for tumors.

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