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Principles of Nephrology
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Glomerulus
A network of capillaries located at the beginning of a nephron in the kidney which filters blood to form urine.
Nephron
The functional unit of the kidney, responsible for removing waste from the blood and producing urine.
Renin-Angiotensin-Aldosterone System (RAAS)
A hormone system that regulates blood pressure and fluid balance through the production of renin, angiotensin, and aldosterone.
Acute Kidney Injury (AKI)
A sudden episode of kidney failure or kidney damage that happens within a few hours or days.
Chronic Kidney Disease (CKD)
A long-term condition characterized by a gradual loss of kidney function over time.
Estimated Glomerular Filtration Rate (eGFR)
A calculation based on a serum creatinine blood test that estimates the rate at which the kidneys filter blood.
Dialysis
A medical procedure that removes waste products and excess fluid from the blood when the kidneys can no longer do so.
Proteinuria
The presence of excess proteins in the urine, which can be a sign of kidney damage.
Hematuria
The presence of blood in the urine, which can indicate urinary tract or kidney damage.
Hyperfiltration
Increased filtration rate of the glomeruli, which can lead to kidney damage over time.
Nephrolithiasis
The medical term for kidney stones, which are solid masses made of crystals that form in the kidneys.
Nephrotic Syndrome
A kidney disorder causing the body to excrete too much protein in the urine.
Azotemia
A medical condition characterized by abnormally high levels of nitrogen-containing compounds in the blood.
Polycystic Kidney Disease (PKD)
A genetic disorder characterized by the growth of numerous cysts in the kidneys.
Uremia
A condition associated with the accumulation of waste products in the blood due to renal failure.
Interstitial Nephritis
An inflammation of the kidney's tubules and surrounding structures, which can lead to acute or chronic kidney failure.
Glomerulonephritis
A range of kidney diseases that involve inflammation of the glomeruli.
Renal Tubular Acidosis (RTA)
A medical disorder in which the kidneys fail to excrete acids into the urine, leading to a blood acidosis condition.
Hemodialysis
A treatment for kidney failure that uses a machine to filter blood outside the body.
Continuous Renal Replacement Therapy (CRRT)
A slower form of dialysis for patients who are hemodynamically unstable, typically used in the intensive care unit.
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