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Principles of Nephrology

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Renin-Angiotensin-Aldosterone System (RAAS)

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A hormone system that regulates blood pressure and fluid balance through the production of renin, angiotensin, and aldosterone.

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Nephrolithiasis

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The medical term for kidney stones, which are solid masses made of crystals that form in the kidneys.

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Proteinuria

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The presence of excess proteins in the urine, which can be a sign of kidney damage.

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Azotemia

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A medical condition characterized by abnormally high levels of nitrogen-containing compounds in the blood.

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Nephron

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The functional unit of the kidney, responsible for removing waste from the blood and producing urine.

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Continuous Renal Replacement Therapy (CRRT)

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A slower form of dialysis for patients who are hemodynamically unstable, typically used in the intensive care unit.

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Estimated Glomerular Filtration Rate (eGFR)

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A calculation based on a serum creatinine blood test that estimates the rate at which the kidneys filter blood.

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Uremia

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A condition associated with the accumulation of waste products in the blood due to renal failure.

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Hemodialysis

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A treatment for kidney failure that uses a machine to filter blood outside the body.

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Glomerulus

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A network of capillaries located at the beginning of a nephron in the kidney which filters blood to form urine.

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Interstitial Nephritis

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An inflammation of the kidney's tubules and surrounding structures, which can lead to acute or chronic kidney failure.

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Renal Tubular Acidosis (RTA)

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A medical disorder in which the kidneys fail to excrete acids into the urine, leading to a blood acidosis condition.

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Dialysis

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A medical procedure that removes waste products and excess fluid from the blood when the kidneys can no longer do so.

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Glomerulonephritis

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A range of kidney diseases that involve inflammation of the glomeruli.

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Polycystic Kidney Disease (PKD)

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A genetic disorder characterized by the growth of numerous cysts in the kidneys.

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Acute Kidney Injury (AKI)

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A sudden episode of kidney failure or kidney damage that happens within a few hours or days.

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Chronic Kidney Disease (CKD)

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A long-term condition characterized by a gradual loss of kidney function over time.

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Hyperfiltration

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Increased filtration rate of the glomeruli, which can lead to kidney damage over time.

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Hematuria

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The presence of blood in the urine, which can indicate urinary tract or kidney damage.

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Nephrotic Syndrome

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A kidney disorder causing the body to excrete too much protein in the urine.

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