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Major works include the Mona Lisa, The Last Supper, and Vitruvian Man. He exemplified the Renaissance humanist ideal and made substantial discoveries in anatomy, optics, and hydraulics.

Major works include the Sistine Chapel ceiling, David, and Pietà. Michelangelo was a poet as well as an architect, influencing the Renaissance with his majestic art and sculpture.

Major works include The School of Athens, the Raphael Rooms, and his numerous Madonna paintings. Raphael's compositions are considered a pinnacle of Renaissance art.

Major works include the bronze David, The Equestrian Statue of Gattamelata, and the marble Saint George. Donatello's work is noted for its realism and detailed human expression.

Major works include The Birth of Venus, Primavera, and Adoration of the Magi. Botticelli's art is known for its linear grace and mythological themes.

Major works include Venus of Urbino, Assumption of the Virgin, and Bacchus and Ariadne. Titian is known for his rich coloration and voluptuous figures.

Major works include Melencolia I, The Apocalypse series, and his self-portraits. Dürer brought the Italian Renaissance influences to Northern Europe and advanced printmaking.

Major works include The Garden of Earthly Delights, The Haywain Triptych, and The Last Judgment. Bosch is known for his surreal and fantastical imagery.

Major works include The Tower of Babel, The Hunters in the Snow, and Peasant Wedding. Bruegel's work focuses on landscapes and daily peasant life, depicting the rhythms of the natural world.