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Basic Endocrinology in Exercise
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Insulin
Helps store glucose and fatty acids; enhances nutrient absorption into cells, crucial for recovery.
Glucagon
Promotes the release of glucose from liver glycogen stores to increase blood glucose.
Leptin
Signals satiety to the brain and can increase energy expenditure.
Epinephrine (Adrenaline)
Increases heart rate and stroke volume, mobilizes energy stores, and enhances muscle contraction.
Testosterone
Promotes muscle protein synthesis and growth, increases muscle size and strength.
Ghrelin
Stimulates appetite and growth hormone release; also plays a role in energy balance.
Norepinephrine (Noradrenaline)
Constricts blood vessels to increase blood pressure, breaks down fat, and increases alertness.
Growth Hormone (GH)
Stimulates muscle growth and repair, bone formation, and fat utilization.
Cortisol
Increases protein breakdown, provides fuel by gluconeogenesis and lipolysis during prolonged exercise.
Thyroid Hormones (T3 & T4)
Regulates basal metabolic rate, important for overall energy balance and weight management.
Adiponectin
Increases insulin sensitivity and fatty acid oxidation; protective against inflammation and atherosclerosis.
Estrogen
Plays a role in muscle repair and bone density maintenance; may affect fat distribution.
Insulin-like Growth Factor 1 (IGF-1)
Mediates the effects of growth hormone, stimulating cell growth and development.
Progesterone
Supports musculoskeletal regeneration and may help to stabilize joints.
Aldosterone
Regulates sodium and water balance, which affects blood volume and pressure.
Arginine Vasopressin (AVP) or Antidiuretic Hormone (ADH)
Promotes water reabsorption in the kidneys, raising blood volume and pressure.
Erythropoietin (EPO)
Stimulates red blood cell production, increasing oxygen transport and aerobic capacity.
Interleukins
Involved in the regulation of the immune system response to exercise and muscle damage.
Myostatin
Inhibits muscle differentiation and growth, thus limiting muscle size and adaptations.
Glucocorticoids
Involved in glucose metabolism, anti-inflammatory response, and suppression of the immune system.
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