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Basic Endocrinology in Exercise

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Insulin

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Helps store glucose and fatty acids; enhances nutrient absorption into cells, crucial for recovery.

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Glucagon

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Promotes the release of glucose from liver glycogen stores to increase blood glucose.

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Leptin

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Signals satiety to the brain and can increase energy expenditure.

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Epinephrine (Adrenaline)

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Increases heart rate and stroke volume, mobilizes energy stores, and enhances muscle contraction.

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Testosterone

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Promotes muscle protein synthesis and growth, increases muscle size and strength.

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Ghrelin

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Stimulates appetite and growth hormone release; also plays a role in energy balance.

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Norepinephrine (Noradrenaline)

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Constricts blood vessels to increase blood pressure, breaks down fat, and increases alertness.

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Growth Hormone (GH)

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Stimulates muscle growth and repair, bone formation, and fat utilization.

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Cortisol

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Increases protein breakdown, provides fuel by gluconeogenesis and lipolysis during prolonged exercise.

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Thyroid Hormones (T3 & T4)

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Regulates basal metabolic rate, important for overall energy balance and weight management.

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Adiponectin

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Increases insulin sensitivity and fatty acid oxidation; protective against inflammation and atherosclerosis.

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Estrogen

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Plays a role in muscle repair and bone density maintenance; may affect fat distribution.

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Insulin-like Growth Factor 1 (IGF-1)

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Mediates the effects of growth hormone, stimulating cell growth and development.

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Progesterone

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Supports musculoskeletal regeneration and may help to stabilize joints.

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Aldosterone

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Regulates sodium and water balance, which affects blood volume and pressure.

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Arginine Vasopressin (AVP) or Antidiuretic Hormone (ADH)

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Promotes water reabsorption in the kidneys, raising blood volume and pressure.

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Erythropoietin (EPO)

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Stimulates red blood cell production, increasing oxygen transport and aerobic capacity.

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Interleukins

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Involved in the regulation of the immune system response to exercise and muscle damage.

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Myostatin

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Inhibits muscle differentiation and growth, thus limiting muscle size and adaptations.

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Glucocorticoids

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Involved in glucose metabolism, anti-inflammatory response, and suppression of the immune system.

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