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Anticoagulant Medications

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Argatroban

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Mechanism of action: Direct thrombin inhibitor, Usage: Anticoagulant for patients with heparin-induced thrombocytopenia, Side effects: Bleeding, anaphylaxis, dysgeusia

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Warfarin

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Mechanism of action: Inhibition of Vitamin K epoxide reductase, Usage: Long-term management of thromboembolic disorders, Side effects: Bleeding, skin necrosis, purple toe syndrome

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Enoxaparin

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Mechanism of action: Low molecular weight heparin, acts by potentiating antithrombin III, Usage: Prevention of DVT and PE, Side effects: Hemorrhage, thrombocytopenia, hyperkalemia

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Apixaban

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Mechanism of action: Selective inhibition of Factor Xa, Usage: Prevention of stroke in patients with non-valvular atrial fibrillation, Side effects: Bleeding, anemia, hypersensitivity reactions

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Dabigatran

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Mechanism of action: Direct thrombin inhibitor, Usage: Prevention of stroke in non-valvular atrial fibrillation, Side effects: Bleeding, dyspepsia, gastritis

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Rivaroxaban

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Mechanism of action: Direct Factor Xa inhibitor, Usage: Treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE), Side effects: Bleeding, liver injury, back pain

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Edoxaban

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Mechanism of action: Selective inhibition of Factor Xa, Usage: Treatment of deep vein thrombosis and pulmonary embolism, Side effects: Bleeding, anemia, rash

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Heparin

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Mechanism of action: Potentiates the activity of antithrombin III, Usage: Prophylaxis and treatment of venous thrombosis, Side effects: Hemorrhage, thrombocytopenia, osteoporosis

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Fondaparinux

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Mechanism of action: Indirect Factor Xa inhibitor via binding to antithrombin III, Usage: Prevention and treatment of deep vein thrombosis and pulmonary embolism, Side effects: Bleeding, thrombocytopenia, elevated liver enzymes

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Bivalirudin

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Mechanism of action: Direct thrombin inhibitor, Usage: Used as an anticoagulant in patients undergoing percutaneous coronary intervention (PCI), Side effects: Bleeding, back pain, nausea

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