Discover published sets by community

Activated by damage inside the vascular system; Factor XII is activated to XIIa.

Activated by external trauma leading to blood escaping the vascular system; Tissue factor (TF) binds with Factor VII, which is then activated to VIIa.

Begins after intrinsic and extrinsic pathways converge; Factor X is activated to Xa.

Acts as a cofactor for Factor IXa in the intrinsic pathway; aids in activating Factor X.

Activated to IXa in the intrinsic pathway; assists in converting Factor X to Xa.

Activated to Xa in the common pathway; forms part of the prothrombinase complex which converts prothrombin to thrombin.

Activated to VIIa by Tissue Factor (TF) in the extrinsic pathway; helps activate Factor X.

Prothrombin (Factor II) is converted to thrombin (IIa) by the prothrombinase complex.

Converts fibrinogen to fibrin, activates platelets, and amplifies coagulation by feedback activation of factors V, VIII, and XI.

Thrombin cleaves fibrinogen to form fibrin, which then polymerizes and crosslinks to form a stable clot.

Activated by thrombin to XIIIa; crosslinks fibrin to stabilize clot.

Inhibits Factor Xa and the complex of tissue factor and Factor VIIa, modulating the extrinsic pathway.

Inactivates thrombin and other serine proteases in the coagulation cascade; its activity is enhanced by heparin.