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Exocrine glands; Management includes saliva substitutes, artificial tears, and immunosuppressive agents.

Spine, sacroiliac joints; Management includes NSAIDs, TNF inhibitors, and physical therapy.

Adrenal glands; Management includes lifelong hormone replacement with glucocorticoids and mineralocorticoids.

Liver, bile ducts; Management includes endoscopic procedures and liver transplantation in advanced cases.

Pancreatic islets; Management includes insulin replacement, diet, and blood glucose monitoring.

Central nervous system; Management includes immunomodulatory therapy, steroids for acute relapses, and symptom management.

Skin, joints (psoriatic arthritis); Management includes topical therapies, phototherapy, and systemic agents.

Thyroid; Management includes thyroid hormone replacement and monitoring of thyroid function.

Neuromuscular junction; Management includes acetylcholinesterase inhibitors, immunosuppressants, and thymectomy.

Small intestine; Management includes a strict gluten-free diet and nutritional support.

Stomach, blood; Management includes vitamin B12 injections or high oral doses of B12.

Blood vessels; Management includes corticosteroids, immunosuppressants, and biologic agents.

Blood vessels, risk of thrombosis; Management includes anticoagulation and monitoring for clotting events.

Liver; Management includes corticosteroids and azathioprine.

Skin, internal organs; Management includes immunosuppressive drugs, vasodilators, and symptomatic treatment.

Blood vessels (temporal arteries); Management includes high-dose corticosteroids and tocilizumab.

Skin, muscles; Management includes corticosteroids, immunosuppressants, and protective measures against sunlight.

Peripheral nervous system; Management includes immunoglobulin therapy, plasmapheresis, and supportive care.

Respiratory tract, kidneys; Management includes corticosteroids and cyclophosphamide.

Joints; Management includes DMARDs, anti-inflammatory drugs, and physiotherapy.

Liver; Management includes ursodeoxycholic acid and sometimes liver transplantation.

Kidneys, lungs; Management includes plasmapheresis, immunosuppressive drugs, and sometimes kidney transplant.

Blood vessels, mucous membranes, skin; Management includes immunosuppressants, corticosteroids, and symptomatic treatment for oral and genital ulcers.

Gastrointestinal tract; Management includes anti-inflammatory drugs, immunosuppressants, and sometimes surgery.

Skin, mucous membranes; Management includes corticosteroids, immunosuppressants, and rituximab.

Skin, joints, kidneys, heart, brain; Management includes NSAIDs, corticosteroids, and antimalarials.

Thyroid; Management includes antithyroid drugs, radioactive iodine, and sometimes surgery.

Blood; Management includes corticosteroids, immunosuppressants, and sometimes splenectomy.

Skeletal muscles; Management includes corticosteroids and DMARDs.