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Serological Markers in Rheumatology

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Antinuclear Antibodies (ANA)

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Systemic Lupus Erythematosus (SLE), Mixed Connective Tissue Disease (MCTD), Drug-induced Lupus

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Anti-Cyclic Citrullinated Peptide (Anti-CCP) Antibodies

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Rheumatoid Arthritis (RA)

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Rheumatoid Factor (RF)

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Rheumatoid Arthritis (RA), Sjögren's Syndrome, Hepatitis C infection

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Antineutrophil Cytoplasmic Antibodies (ANCAs)

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Granulomatosis with Polyangiitis (Wegener's Granulomatosis), Microscopic Polyangiitis, Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome)

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Anti-Scl-70 (Anti-Topoisomerase I) Antibodies

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Systemic Sclerosis (Scleroderma)

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Anti-Cardiolipin Antibodies

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Antiphospholipid Syndrome (APS), Systemic Lupus Erythematosus (SLE)

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Anti-Sm Antibodies

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Systemic Lupus Erythematosus (SLE)

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Anti-dsDNA Antibodies

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Systemic Lupus Erythematosus (SLE)

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Anti-Ro/SSA and Anti-La/SSB Antibodies

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Sjögren's Syndrome, Systemic Lupus Erythematosus (SLE), Neonatal Lupus

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Beta-2 Glycoprotein I Antibodies

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Antiphospholipid Syndrome (APS)

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Anticentromere Antibodies

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Limited Cutaneous Systemic Sclerosis (CREST Syndrome)

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Anti-U1 RNP Antibodies

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Mixed Connective Tissue Disease (MCTD), Systemic Lupus Erythematosus (SLE)

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Anti-Jo-1 Antibodies

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Polymyositis, Dermatomyositis

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Anti-PL-7 and Anti-PL-12 Antibodies

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Anti-synthetase syndrome

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Anti-Ku Antibodies

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Mixed Connective Tissue Disease (MCTD), Systemic Sclerosis (Scleroderma)

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Anti-Ribosomal P Protein Antibodies

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Systemic Lupus Erythematosus (SLE)

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Anti-Mi-2 Antibodies

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Dermatomyositis

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Lupus Anticoagulant

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Antiphospholipid Syndrome (APS), Systemic Lupus Erythematosus (SLE)

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Anti-SRP Antibodies

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Polymyositis

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HLA-B27

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Ankylosing Spondylitis, Reactive Arthritis, Psoriatic Arthritis

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Anti-PM-Scl Antibodies

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Polymyositis/Scleroderma Overlap Syndrome

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Complement Levels (C3, C4)

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Systemic Lupus Erythematosus (SLE), Infections, Liver disease

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Anti-Smith (Anti-Sm) Antibodies

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Systemic Lupus Erythematosus (SLE)

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Cryoglobulins

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Cryoglobulinemia, Hepatitis C, B-cell Dyscrasias

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CCP (Cyclic Citrullinated Peptide) Antibody

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Rheumatoid Arthritis (RA)

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