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Basic Rheumatology Terminology
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Gout
A type of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint, caused by elevated levels of uric acid in the blood.
Raynaud's Phenomenon
A vascular disorder causing discoloration of the fingers, toes, and occasionally other areas, due to an excessive response to cold or stress.
Seronegative
Refers to diseases where the characteristic autoantibodies are absent, often seen in certain types of arthritis.
Spondyloarthropathy
A group of inflammatory diseases that involve both the joints and the entheses (sites where the ligaments and tendons attach to bones).
Mixed Connective Tissue Disease (MCTD)
A rare autoimmune disorder with overlapping features of lupus, scleroderma, and polymyositis, and uniquely characterized by high levels of anti-U1 RNP antibodies.
Uveitis
Inflammation of the uvea, the middle layer of the eye that consists of the iris, ciliary body, and choroid.
RF
Rheumatoid Factor
HLA-B27
Human Leukocyte Antigen B27
DMARDs
Disease-Modifying Antirheumatic Drugs
Myositis
Inflammation of the muscles, which can cause muscle weakness and pain.
Behcet's Disease
A rare disorder causing inflammation in blood vessels throughout the body.
CRP
C-Reactive Protein
Enthesitis
Inflammation of the entheses, the sites where tendons or ligaments insert into the bone.
Chondritis
Inflammation of the cartilage.
Vasculitis
Inflammation of the blood vessels that can cause vessel walls to thicken, narrow, weaken, or scar, affecting flow of blood throughout the body.
Pannus
An abnormal layer of fibrovascular tissue or granulation tissue, common in rheumatoid arthritis, that spreads over joint surfaces and causes cartilage erosion.
CPPD
Calcium Pyrophosphate Deposition Disease
Reactive Arthritis
An autoimmune condition that develops in response to an infection in another part of the body (cross-reactivity).
Synovitis
Inflammation of the synovial membrane, the lining of the joint.
Scleroderma
A group of rare, progressive diseases that involve the hardening and tightening of the skin and connective tissues.
Bouchard's Nodes
Bony enlargements on the middle joints of fingers, often associated with osteoarthritis.
OA
Osteoarthritis
ANA
Antinuclear Antibody
Fibromyalgia
A condition characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory, and mood issues.
Anti-CCP
Anti-Cyclic Citrullinated Peptide antibody
Heberden's Nodes
Bony enlargements of the small joints at the distal end of the fingers commonly associated with osteoarthritis.
Dactylitis
Inflammation of the fingers or toes which may present as swelling giving a sausage-like appearance, often seen in psoriatic arthritis and other spondyloarthropathies.
PsA
Psoriatic Arthritis
Antiphospholipid Syndrome
An autoimmune disorder characterized by blood clots and pregnancy complications, associated with antiphospholipid antibodies.
Henoch-Schonlein Purpura (HSP)
A disease involving inflammation of small blood vessels, causing them to bleed into the skin, joints, intestines, and kidneys.
RA
Rheumatoid Arthritis
SLE
Systemic Lupus Erythematosus
Septic Arthritis
The infection of a joint, usually caused by bacteria, which can lead to rapid joint destruction.
Takayasu's Arteritis
A rare form of vasculitis that affects large and medium-sized arteries, particularly the aorta and its main branches.
TNF
Tumor Necrosis Factor
Polymyalgia Rheumatica
An inflammatory disorder causing muscle pain and stiffness, most commonly in the shoulders and hips, often associated with giant cell arteritis.
Lupus Nephritis
An inflammation of the kidneys caused by systemic lupus erythematosus.
Polychondritis
A rare multisystem disorder characterized by recurrent inflammation of cartilage and other tissues throughout the body.
Sjogren's Syndrome
A chronic autoimmune disease characterized by dry eyes and dry mouth.
Caplan's Syndrome
A rare condition involving lung nodules in individuals with rheumatoid arthritis who have had significant exposure to coal dust.
Baker's Cyst
A fluid-filled cyst that causes a bulge and a feeling of tightness behind the knee.
Costochondritis
Inflammation of the cartilage that connects a rib to the sternum (breastbone).
Still's Disease
A rare inflammatory disorder characterized by high fevers, rash, and joint pain that may progress to chronic arthritis.
AS
Ankylosing Spondylitis
Tophi
Deposits of monosodium urate crystals in people with longstanding hyperuricemia (which results in gout).
ESR
Erythrocyte Sedimentation Rate
Scleritis
A serious inflammation of the sclera, the white outer coating of the eye, often associated with autoimmune diseases.
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