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Rheumatoid Arthritis Medications

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Sarilumab

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Common uses: Rheumatoid arthritis; Side effects: Infections, neutropenia, liver enzyme elevation; Drug class: Interleukin-6 (IL-6) receptor antagonist

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Cyclosporine

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Common uses: Severe rheumatoid arthritis, organ transplant rejection prophylaxis; Side effects: Renal dysfunction, hypertension, gingival hyperplasia; Drug class: Calcineurin inhibitor

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Certolizumab pegol

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Common uses: Rheumatoid arthritis, Crohn's disease; Side effects: Infections, hypertension, headache; Drug class: TNF alpha inhibitor

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Golimumab

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Common uses: Rheumatoid arthritis, ankylosing spondylitis; Side effects: Infections, injection site reactions, headache; Drug class: TNF alpha inhibitor

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Hydroxychloroquine

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Common uses: Rheumatoid arthritis, lupus; Side effects: Nausea, retinal damage, skin rash; Drug class: Antimalarial DMARD

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Infliximab

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Common uses: Rheumatoid arthritis, Crohn's disease; Side effects: Infusion reactions, infections, antibody development; Drug class: TNF alpha inhibitor

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Secukinumab

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Common uses: Psoriatic arthritis, ankylosing spondylitis; Side effects: Infections, diarrhea, upper respiratory tract infection; Drug class: IL-17A inhibitor

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Leflunomide

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Common uses: Rheumatoid arthritis; Side effects: Diarrhea, liver toxicity, hair loss; Drug class: Pyrimidine synthesis inhibitor

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Diclofenac

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Common uses: Rheumatoid arthritis, osteoarthritis, acute pain; Side effects: Gastrointestinal bleeding, hepatotoxicity, increased blood pressure; Drug class: Non-selective NSAID

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Prednisone

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Common uses: Rheumatoid arthritis flare management, chronic immunosuppression; Side effects: Weight gain, osteoporosis, increased blood sugar; Drug class: Corticosteroid

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Penicillamine

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Common uses: Rheumatoid arthritis, Wilson's disease; Side effects: Bone marrow suppression, proteinuria, skin reactions; Drug class: Chelating agent

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Baricitinib

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Common uses: Rheumatoid arthritis; Side effects: Infections, increased cholesterol, nausea; Drug class: JAK inhibitor

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Abatacept

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Common uses: Rheumatoid arthritis; Side effects: Headache, infections, nausea; Drug class: Selective costimulation modulator

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Sulfasalazine

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Common uses: Rheumatoid arthritis, ulcerative colitis; Side effects: Headache, gastrointestinal upset, rash; Drug class: Sulfonamide DMARD

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Rituximab

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Common uses: Rheumatoid arthritis, non-Hodgkin's lymphoma; Side effects: Infusion reactions, infections, cytopenias; Drug class: CD20-directed cytolytic antibody

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Tocilizumab

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Common uses: Rheumatoid arthritis; Side effects: Infections, elevated liver enzymes, hypertension; Drug class: Interleukin-6 (IL-6) inhibitor

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Etanercept

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Common uses: Rheumatoid arthritis, psoriatic arthritis; Side effects: Injection site reactions, infections, dizziness; Drug class: TNF alpha inhibitor

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Anakinra

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Common uses: Rheumatoid arthritis, cryopyrin-associated periodic syndromes; Side effects: Injection site reactions, infections, headache; Drug class: IL-1 receptor antagonist

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Azathioprine

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Common uses: Rheumatoid arthritis, inflammatory bowel disease; Side effects: Bone marrow suppression, hepatotoxicity, increased risk of infection; Drug class: Purine synthesis inhibitor

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Ibuprofen

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Common uses: Rheumatoid arthritis, osteoarthritis, fever reduction; Side effects: Gastrointestinal bleeding, renal impairment, hypersensitivity reactions; Drug class: Non-selective NSAID

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Adalimumab

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Common uses: Rheumatoid arthritis, other autoimmune diseases; Side effects: Injection site reactions, infections, headache; Drug class: TNF alpha inhibitor

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Tofacitinib

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Common uses: Rheumatoid arthritis, psoriatic arthritis; Side effects: Infections, increased cholesterol, headache; Drug class: JAK inhibitor

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Methotrexate

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Common uses: Rheumatoid arthritis, psoriasis; Side effects: Nausea, mouth sores, elevated liver enzymes; Drug class: Disease-Modifying Antirheumatic Drug (DMARD)

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Peficitinib

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Common uses: Rheumatoid arthritis; Side effects: Infections, nausea, increased blood pressure; Drug class: JAK inhibitor

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Ixabepilone

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Common uses: Not typically used for rheumatoid arthritis; Side effects: Peripheral neuropathy, myelosuppression, gastrointestinal symptoms; Drug class: Antineoplastic agent

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Celecoxib

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Common uses: Rheumatoid arthritis, osteoarthritis, acute pain; Side effects: Gastrointestinal ulceration, cardiovascular risk, renal impairment; Drug class: COX-2 selective NSAID

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Naproxen

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Common uses: Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis; Side effects: Gastrointestinal ulceration, renal impairment, cardiovascular risk; Drug class: Non-selective NSAID

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Upadacitinib

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Common uses: Rheumatoid arthritis; Side effects: Infections, elevated liver enzymes, nausea; Drug class: JAK inhibitor

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Apremilast

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Common uses: Psoriatic arthritis, plaque psoriasis; Side effects: Diarrhea, weight loss, depression; Drug class: Phosphodiesterase 4 inhibitor

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