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The malar rash, also known as the butterfly rash, is a classic skin manifestation of SLE.

Corticosteroids are used in SLE for their potent anti-inflammatory and immunosuppressive effects.

ANA test is commonly positive in SLE patients and is often used as a screening tool.

Patients with SLE are advised to avoid sun exposure as it can worsen skin lesions and trigger flares.

SLE can affect pregnancy outcomes and requires close monitoring for both the mother and fetus.

Biological agents, such as Belimumab, target specific components of the immune system to control SLE.

SLE can cause various blood disorders including anemia, leukopenia, thrombocytopenia, and antiphospholipid syndrome.

Sjogren's syndrome is a common overlap condition in SLE, characterized by dry eyes and dry mouth.

Regular monitoring with blood tests, urine tests, and clinical assessments is necessary to assess disease activity and organ involvement in SLE.

Anti-dsDNA antibodies are more specific for SLE and correlate with disease activity.

Symptoms include fatigue, joint pain, rash, and fevers.

SLE increases the risk of cardiovascular diseases, hence monitoring and preventive strategies are important.

Topical corticosteroids and immunomodulators, as well as antimalarial drugs, can be used to treat lupus-related skin lesions.

Women with SLE need careful selection of contraception to avoid hormonal influences that can contribute to flares.

The ACR criteria include malar rash, discoid rash, photosensitivity, oral ulcers, arthritis, serositis, renal disorder, neurological disorder, hematological disorder, immunological disorder, and presence of antinuclear antibodies.

Environmental factors, such as UV light, infections, and stress, can trigger lupus flares.

Complementary approaches, such as diet modification, stress reduction, and physical therapy, can support medical treatment of SLE.

Systemic Lupus Erythematosus (SLE) is an autoimmune disease where the immune system attacks healthy tissue.

Treatment may include NSAIDs, corticosteroids, antimalarials, DMARDs, and biological agents.

Discoid lupus is a chronic skin condition associated with SLE, characterized by disc-shaped, scaly, red patches.

Nervous system involvement in SLE can manifest as seizures, psychosis, and cognitive dysfunction.

Pleural effusion and pneumonitis are potential pulmonary manifestations of SLE.

Lupus nephritis is kidney inflammation caused by SLE and requires a renal biopsy for diagnosis.

Flare management includes increasing medication doses, rest, and avoiding triggers such as sunlight.