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Sjögren's Syndrome Insights

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Dry Eyes (Xerophthalmia)

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Caused by decreased tear production. Management includes artificial tears and moisture chamber spectacles.

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Dry Mouth (Xerostomia)

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Results from reduced salivary flow. Management entails sipping water regularly, using saliva substitutes, and good oral hygiene.

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Raynaud's Phenomenon

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Characterized by episodic vasospasm in extremities. Management includes keeping warm, avoiding stress and smoking, and vasodilator drugs if severe.

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Fatigue

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A pervasive and disabling symptom. Management focuses on pacing activities, getting adequate rest, and possibly cognitive-behavioral therapy.

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Interstitial Lung Disease

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Can occur in advanced cases. Treatment includes corticosteroids and immunosuppressive agents.

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Keratoconjunctivitis Sicca

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A form of chronic dry eye. Diagnosed with Schirmer's test or tear break-up time test; treated with cyclosporine eye drops or punctal plugs.

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Joint Pain (Arthralgia) and Swelling

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Commonly affects small joints. Managed with NSAIDs, corticosteroids or DMARDs for more severe cases.

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Dry Skin (Xerosis)

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Often due to decreased moisture. Use of moisturizers and mild soaps can help maintain skin hydration.

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Swollen Salivary Glands

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Usually the parotid gland. Managed with good oral hygiene, massage, and sometimes corticosteroids or immunosuppressants for inflammation.

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Peripheral Neuropathy

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Nerve dysfunction can cause numbness and tingling. Managed with pain medication, tricyclic antidepressants, and anticonvulsants for neuropathic pain.

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Oral Candidiasis

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Yeast infections in the mouth due to salivary gland dysfunction. Antifungal medications and good oral hygiene practices are the mainstay of treatment.

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Lymphoma

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Increased risk in Sjögren's patients. Monitoring and treatment depend on the type and stage of lymphoma, often involves chemotherapy or immunotherapy.

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Dental Caries

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Due to dry mouth, risk of dental decay increases. Prevention through fluoride treatments and meticulous dental care is key.

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Vaginal Dryness

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Can lead to dyspareunia (painful intercourse). Vaginal moisturizers and lubricants, along with estrogen therapy, can alleviate symptoms.

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Persistent Dry Cough

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Results from dryness in the respiratory tract. Staying hydrated and using expectorants can be beneficial.

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