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Microbiota and Human Health

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Firmicutes

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Associated with energy harvest from diet; alterations can affect obesity and metabolic health.

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Veillonella spp.

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Associated with lactate metabolism and oral health; may influence athletic performance.

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Lactococcus lactis

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Important in dairy fermentation; engineered strains used in the production of pharmaceuticals.

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Enterococcus faecalis

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Normal gut inhabitant but can be an opportunistic pathogen, especially in hospital settings.

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Candida albicans

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Overgrowth can cause candidiasis; normal presence contributes to mucosal immunity.

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Saccharomyces boulardii

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A yeast probiotic that can prevent and treat gastrointestinal disorders like diarrhea.

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Escherichia coli

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Synthesizes vitamin K and helps in the digestion of certain food components.

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Roseburia spp.

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Butyrate-producing bacteria associated with gut health and possibly with protecting against colorectal cancer.

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Bacteroides fragilis

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Protects against intestinal inflammation and is involved in the development of the immune system.

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Klebsiella spp.

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Part of the normal microbiota but can cause infections if they spread to other parts of the body.

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Blautia spp.

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Associated with the fermentation of carbohydrates and the production of beneficial short-chain fatty acids.

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Methanobrevibacter smithii

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A methanogen that helps to optimize digestion by removing excess hydrogen gas.

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Prevotella spp.

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Dominant in individuals with high-fiber diets; potential role in rheumatoid arthritis.

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Akkermansia muciniphila

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Promotes a healthy mucosal layer in the gut and linked with improved metabolic profiles.

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Faecalibacterium prausnitzii

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Anti-inflammatory effects and associated with healthy gut flora; low levels linked to Crohn's disease.

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Helicobacter pylori

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Linked to peptic ulcers and stomach cancer but also regulates stomach acidity.

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Staphylococcus epidermidis

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Protects skin by outcompeting pathogens, but can also cause nosocomial infections.

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Bifidobacterium spp.

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Supports gut barrier function, enhances digestion, and modulates the immune system.

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Lactobacillus spp.

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Aids digestion, boosts immune system, and inhibits pathogenic bacteria growth.

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Streptococcus mutans

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Major contributor to dental caries through production of lactic acid from sugar.

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Ruminococcus spp.

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Fermentation of dietary fibers, production of short-chain fatty acids, and potential impact on gut motility.

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Streptococcus thermophilus

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Used in the production of yogurt and cheeses; supports lactose digestion and gut health.

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Clostridium difficile

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Can lead to severe diarrhea and colitis, often following antibiotic therapy.

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Bacteroidetes

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Crucial for the breakdown of complex carbohydrates; imbalance linked to inflammation and obesity.

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Propionibacterium acnes

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Associated with acne development, but also decomposes skin oils and prevents pathogen colonization.

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