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Neuroplasticity

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Neurogenesis

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Neurogenesis is the process by which new neurons are formed in the brain. Example: The hippocampus is known to generate new neurons throughout a person's life.

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Synaptic Plasticity

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Synaptic plasticity is the ability of synapses to strengthen or weaken over time, in response to increases or decreases in their activity. Example: Long-term potentiation (LTP) at glutamatergic synapses, which is essential for learning and memory.

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Long-term Potentiation (LTP)

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Long-term potentiation (LTP) is a long-lasting enhancement in signal transmission between two neurons that results from their simultaneous activation. Example: LTP is a major cellular mechanism behind learning and memory.

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Competitive Plasticity

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Competitive plasticity is the concept that synaptic connections will become stronger with frequent activation and survive, while rarely activated synapses will weaken and may eventually be pruned. Example: Dominant use of one language can reduce the synaptic strength for another language if not used frequently.

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Brain-derived Neurotrophic Factor (BDNF)

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BDNF is a protein that supports the survival of existing neurons and encourages the growth and differentiation of new neurons and synapses. Example: BDNF levels increase with exercise, which can lead to improved cognitive function.

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Structural Plasticity

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Structural plasticity refers to the brain's ability to physically change its structure in response to learning, experience, or environment. Example: Changes in dendritic spines during learning and memory tasks.

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Functional Plasticity

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Functional plasticity is the brain's ability to move functions from a damaged area of the brain to undamaged areas. Example: Stroke patients often recover abilities as other areas of the brain take over functions of the damaged tissue.

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Use-dependent Plasticity

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Use-dependent plasticity is a form of plasticity where the brain changes as a consequence of task repetition and practice. Example: Typists have larger and more developed hand regions in the brain's somatosensory cortex.

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Experience-dependent Plasticity

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Experience-dependent plasticity is the continuous process by which the brain changes and reorganizes itself based on sensory experiences throughout a person's life. Example: Learning to play a musical instrument changes motor areas responsible for controlling relevant muscles.

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Cortical Remapping

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Cortical remapping refers to the process by which the functional map of the brain's cortex changes, often in response to injury, learning, or experience. Example: When a limb is amputated, other sensory areas may expand into the area that was once devoted to that limb.

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Neuroplasticity

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Neuroplasticity, also known as brain plasticity, is the ability of the neural networks in the brain to change through growth and reorganization. Example: After a stroke, other parts of the brain could take over the functions of the damaged areas.

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Long-term Depression (LTD)

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Long-term depression (LTD) is a long-lasting decrease in synaptic strength that occurs with less frequent activation of a synaptic connection. Example: LTD can undo LTP, which can reset connections to a baseline state for new learning.

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Mirror Neurons

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Mirror neurons are neurons that fire both when an animal acts and when the animal observes the same action performed by another. Example: Mirroring systems may help us understand actions and intentions of others, playing a role in empathy and learning by imitation.

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Pruning

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Pruning is the process of synapse elimination that occurs between early childhood to the onset of puberty in humans, helping to streamline the structure of neural networks. Example: The reduction of gray matter during the teenage years as the brain becomes more specialized.

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Hebbian Theory

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Hebbian Theory is a theory that proposes an explanation for synaptic plasticity, wherein an increase in synaptic efficacy arises from the presynaptic cell's repeated and persistent stimulation of the postsynaptic cell. Example: 'Cells that fire together, wire together.'

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