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Cobalt-Chromium Alloys
Properties: High wear and corrosion resistance, biocompatibility. Advantages: High stiffness, can withstand high stress, suitable for casting. Applications: Hip and knee implants, dental prostheses, pacemaker leads.
Dacron (Polyethylene Terephthalate, PET)
Properties: High tensile strength, resistance to biodegradation, stability under stress. Advantages: Proven track record in cardiovascular applications, can be woven into fabric, low creep under load. Applications: Vascular grafts, heart valves, artificial ligaments and tendons.
Polyethylene
Properties: Chemical resistance, toughness, low friction. Advantages: Easy to process, low cost, available in high molecular weight variants. Applications: Artificial joints, vascular grafts, cartilage replacements.
Hydrogels
Properties: High water content, permeability to metabolites, soft and pliable. Advantages: Can provide a moist environment, mimic natural tissue elasticity, promote cell adherence. Applications: Wound dressings, contact lenses, tissue engineering scaffolds.
Polycaprolactone (PCL)
Properties: Biodegradability, good mechanical properties, relatively slow degradation. Advantages: Good blend compatibility with other polymers, low melting point, FDA approved for certain uses. Applications: Long-term implantable devices, drug delivery systems, scaffold material for tissue engineering.
Bioactive Glass
Properties: Bonding to bone and soft tissue, stimulates biological processes, highly biocompatible. Advantages: Can be tailored for different degradation rates, encourages cellular response, osteoproductive. Applications: Bone regeneration, dentin regeneration, as a scaffold in tissue engineering.
Polyurethane
Properties: Elasticity, tensile strength, abrasion resistance. Advantages: Versatile - can be rigid or flexible, good blood compatibility, wide range of hardness. Applications: Vascular grafts, heart valves, catheters.
Stainless Steel
Properties: Corrosion resistance, strength, ductility. Advantages: Easy to fabricate, low cost, resistant to sterilization processes. Applications: Orthopedic implants, surgical instruments, stents.
Silk
Properties: Biocompatibility, biodegradation, mechanical resilience. Advantages: Similar structural properties to some types of collagen, can be processed into various formats, minimal inflammatory response. Applications: Sutures, tissue engineering scaffolds, drug delivery systems.
Silk Fibroin
Properties: Biodegradability, excellent tensile strength, good elasticity. Advantages: Can be processed into various forms, promotes cell adhesion and proliferation, natural protein-based polymer. Applications: Scaffold material for tissue engineering, wound dressings, drug delivery systems.
Graphene
Properties: High electrical and thermal conductivity, mechanical strength, large surface area. Advantages: Can be functionalized, promotes osteogenic differentiation, high sensitivity for sensors. Applications: Biosensors, drug delivery, enhancing mechanical properties of other biomaterials.
Polyvinyl Alcohol (PVA)
Properties: Water soluble, biocompatible, high tensile strength. Advantages: Can be engineered to be porous, good for hydrogel formation, resistant to swelling. Applications: Artificial cartilage, contact lenses, drug delivery systems.
Polyether Ether Ketone (PEEK)
Properties: High mechanical strength, chemical resistance, radiolucent. Advantages: Biological inertness, stability under high stress situations, can be reinforced with carbon fiber. Applications: Spinal fusion devices, skull reconstruction plates, dental implants.
Polyhydroxyalkanoates (PHAs)
Properties: Biodegradability, biocompatibility, thermoplasticity. Advantages: Produced naturally by microorganisms, can be engineered for specific mechanical properties, environmentally friendly. Applications: Drug delivery, medical implants, tissue engineering scaffolds.
Polytetrafluoroethylene (PTFE)
Properties: High chemical and thermal resistance, low coefficient of friction. Advantages: Non-reactive, can be used as a lubricious coating, biocompatible. Applications: Vascular grafts, heart valves, suture materials.
Alginate
Properties: Gel-forming, biocompatible, biodegradable. Advantages: Ability to form hydrogels, favorable for cell encapsulation, can be used for controlled release. Applications: Wound dressings, drug delivery systems, dental impressions.
Dental Amalgam
Properties: High mechanical strength, wear resistance, marginal seal. Advantages: Long track record of use, cost-effective, easy to manipulate. Applications: Dental fillings, particularly for posterior teeth.
Silicone
Properties: Flexibility, thermal stability, inertness. Advantages: Mimics soft tissue, low immunogenicity, resistant to bacteria. Applications: Breast implants, cardiovascular devices, contact lenses.
Bioceramics
Properties: Hardness, wear resistance, ability to bond to bone. Advantages: Chemically stable, can be osteoconductive, non-toxic. Applications: Bone grafts, dental implants, joint replacements.
Chitosan
Properties: Biocompatibility, biodegradability, antibacterial. Advantages: Hemostatic properties, promotes tissue regeneration, can be molded into various shapes. Applications: Drug delivery systems, wound dressings, scaffolds for tissue engineering.
Zirconia
Properties: High fracture toughness, wear resistance, biocompatibility. Advantages: Aesthetic due to its color and translucency, resistant to chemical degradation, does not induce hypersensitivity. Applications: Dental crowns and bridges, hip joint replacements, dental implants.
Gore-Tex (Expanded Polytetrafluoroethylene, ePTFE)
Properties: Porosity, biocompatible, chemically inert. Advantages: Creates a barrier while allowing tissue integration, can be used in contaminated or infected environments, does not degrade. Applications: Vascular grafts, hernia mesh, patches for soft tissue repair.
Kevlar
Properties: High tensile strength, abrasion resistance, thermal stability. Advantages: Lightweight, strong, used in protective equipment. Applications: Not commonly used as a biomaterial due to biocompatibility concerns, research in prostheses, and protective gear for healthcare.
Polymethylmethacrylate (PMMA)
Properties: Transparency, durability, biocompatibility. Advantages: Can be cast and molded, easy to handle and process, commonly used as bone cement. Applications: Intraocular lenses, bone cement, dentures.
Magnesium Alloys
Properties: Biodegradability, light weight, good mechanical properties. Advantages: Bone-like density, gradual biodegradation can reduce stress shielding effect, promotes bone growth. Applications: Orthopedic screws and plates, cardiovascular stents, bone grafts.
Gold
Properties: Good conductivity, ductility, resistance to oxidation and corrosion. Advantages: Biocompatible, easy to work with in fine details, esthetically pleasing. Applications: Dental fillings, implants, electrical contacts in pacemakers.
Titanium
Properties: High strength-to-weight ratio, biocompatibility, corrosion resistance. Advantages: Non-toxic, can integrate with bone, low density. Applications: Dental implants, joint replacements, bone screws.
Calcium Phosphate Ceramics
Properties: Chemical similarity to bone mineral, bioactivity, osteoconductivity. Advantages: Can be shaped before setting, supports bone cell function, versatile with different phases (e.g., tricalcium phosphate). Applications: Bone graft substitutes, dental applications, filler for bone defects.
Poly(lactic-co-glycolic acid) (PLGA)
Properties: Biodegradability, good mechanical properties, tunable degradation rate. Advantages: FDA approved for clinical use, can carry drugs and other bioactive agents, varied applications due to copolymer composition. Applications: Sutures, drug delivery vehicles, tissue engineering scaffolds.
Polyglycolic Acid (PGA)
Properties: High tensile strength, hydrolytic degradation, biocompatibility. Advantages: Supports cell attachment and proliferation, fully biodegradable, used as a surgical suture. Applications: Absorbable sutures, tissue engineering, drug delivery systems.
Polyanhydrides
Properties: Surface erosion upon degradation, biocompatibility, customizable degradation rate. Advantages: Predictable degradation, localized drug delivery, low systemic toxicity. Applications: Chemotherapeutic delivery, vaccine delivery, bone repair.
Collagen
Properties: Biodegradability, good cell attachment, low antigenicity. Advantages: Promotes healing, can be remodeled by body, native ECM protein. Applications: Skin grafts, tissue engineering, wound dressings.
Nitinol
Properties: Shape memory effect, superelasticity, biocompatible. Advantages: Can undergo large deformations and return to original shape, responds to temperature changes. Applications: Self-expanding stents, orthodontic wires, surgical staples.
Bioresorbable Vascular Scaffold
Properties: Temporary support, fully resorbable, promotes healing. Advantages: Reduces long-term complications associated with metal stents, allows vessel restoration to its natural state. Applications: Treatment of coronary artery disease, peripheral artery disease.
Hydroxyapatite
Properties: Osteoconductivity, biocompatibility, similar to mineral component of bone. Advantages: Supports bone in-growth and healing, can be used as a coating to improve implant fixation, non-toxic. Applications: Bone grafts, dental implants, as a coating for metal implants.
Polypropylene (PP)
Properties: Chemical resistance, fatigue resistance, low cost. Advantages: Easy to mold and extrude, sterilizable, lightweight. Applications: Medical containers, syringes, hernia and pelvic floor mesh.
Polycarbonate
Properties: Optical clarity, impact resistance, heat resistance. Advantages: Easily processed, durable, FDA approved for contact with the human body. Applications: Medical devices, face shields, components of medical instrumentation.
Ethylene Vinyl Acetate (EVA)
Properties: Flexibility, low-temperature toughness, UV radiation resistance. Advantages: Can be processed by thermomolding, good cushioning properties, gradually biodegradable in certain formulations. Applications: Drug delivery systems, coatings for wires and cables, ocular implants.
Liquid Crystal Polymers (LCPs)
Properties: High strength, chemical resistance, inherent flame retardance. Advantages: Maintains properties at high temperatures, resistant to stress cracking, excellent barrier properties. Applications: Medical devices that require precision and stability, surgical instruments, advanced prosthetic devices.
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