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Digestive System Hormones

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Peptide YY (PYY)

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Inhibits gastric and pancreatic secretions, slows gastric emptying, and decreases appetite.

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Somatostatin

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Inhibits the release of many other hormones, slows gastric emptying, and reduces gastric acid secretion.

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Secretin

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Stimulates the pancreas to release bicarbonate-rich juice, neutralizing stomach acid entering the small intestine.

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Motilin

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Regulates gastrointestinal motility and initiates migrating motor complexes in the small intestine.

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Gastrin

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Stimulates acid secretion by the stomach, aids in gastric motility, and promotes growth of gastric mucosa.

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Enteroglucagon

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Inhibits gastric acid secretion and motility, and promotes intestinal mucosal growth.

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Ghrelin

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Stimulates appetite and increases gastric motility and acid secretion.

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Insulin

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Regulates blood glucose levels by facilitating cellular glucose uptake and inhibiting glucose production by the liver.

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Glucagon-like peptide-1 (GLP-1)

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Enhances insulin secretion, inhibits glucagon release, slows gastric emptying, and decreases appetite.

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Cholecystokinin (CCK)

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Stimulates the gallbladder to release bile, aids in pancreatic enzyme secretion, and slows gastric emptying.

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Glucagon

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Increases blood glucose levels by stimulating glycogen breakdown and glucose release by the liver.

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Pancreatic polypeptide (PP)

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Regulates pancreatic secretion activities and influences hepatic glycogen levels and gastrointestinal motility.

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