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Addiction Pharmacotherapy
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Disulfiram
Alcohol addiction; It inhibits the enzyme acetaldehyde dehydrogenase, leading to unpleasant effects when alcohol is consumed.
Naltrexone
Alcohol and opioid addiction; It blocks opioid receptors, which reduces pleasure derived from these substances.
Buprenorphine
Opioid addiction; It is a partial opioid agonist, which can reduce cravings and withdrawal symptoms without the high associated with full agonists.
Acamprosate
Alcohol addiction; It stabilizes chemical signaling in the brain that would otherwise be disrupted by alcohol withdrawal.
Methadone
Opioid addiction; It is a full opioid agonist that reduces cravings and withdrawal symptoms without providing the intense high of other opioids.
Nicotine Replacement Therapy (NRT)
Tobacco addiction; Provides nicotine without the harmful constituents of tobacco smoke, to reduce withdrawal symptoms and cravings.
Varenicline (Chantix)
Tobacco addiction; It is a partial agonist at the nicotinic acetylcholine receptor, reducing cravings and the pleasure associated with smoking.
Clonidine
Opioid and alcohol withdrawal; It helps to reduce withdrawal symptoms by affecting blood pressure and calming the sympathetic nervous system.
Baclofen
Alcohol and cocaine addiction; It acts on GABA receptors and may help to reduce cravings and withdrawal symptoms.
Modafinil
Stimulant addiction; This medication may improve mood and reduce the withdrawal symptoms associated with stimulant addiction.
Topiramate
Alcohol addiction; It may help by reducing the dopamine release associated with alcohol consumption, thereby decreasing the rewarding effects of alcohol.
Gabapentin
Alcohol withdrawal; It may alleviate withdrawal symptoms by stabilizing neural excitability.
Lofexidine
Opioid withdrawal; It is an alpha-2 adrenergic receptor agonist that helps reduce withdrawal symptoms such as insomnia, anxiety, and agitation.
Antabuse
Alcohol addiction; It is another name for Disulfiram and works by deterring alcohol consumption through unpleasant effects.
Subutex
Opioid addiction; This is a brand name for Buprenorphine, used as a replacement therapy for opioid dependence.
Suboxone
Opioid addiction; This medication is a combination of Buprenorphine and Naloxone. It provides relief from withdrawal symptoms and reduces the potential for abuse.
Zyban
Tobacco addiction; This is another name for Bupropion, an antidepressant that's used to help people quit smoking by reducing cravings and withdrawal effects.
Methadose
Opioid addiction; It is a brand name for Methadone used in maintenance therapy to help people with opioid dependency avoid withdrawal symptoms.
Revia
Alcohol and opioid addiction; This is a brand name for Naltrexone which is used to prevent relapse into abuse of these substances.
Campral
Alcohol addiction; This is the brand name for Acamprosate, which helps maintain abstinence in people with alcohol dependence.
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