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Used to treat alcohol and opioid dependency. Method of action: Opioid antagonist that blocks the euphoric effects of opioids and reduces the craving for alcohol.

Used to treat opioid dependency. Method of action: Full opioid agonist that activates opioid receptors in the brain, reducing withdrawal symptoms and cravings.

Used to treat opioid addiction. Method of action: Partial opioid agonist that activates opioid receptors but produces a lesser effect, reducing cravings and withdrawal symptoms.

Used to treat alcohol dependence. Method of action: Thought to restore the balance between excitatory and inhibitory neurotransmission.

Used to support the treatment of chronic alcoholism. Method of action: Inhibits the enzyme acetaldehyde dehydrogenase, leading to unpleasant reactions when alcohol is consumed.

Used to treat stimulant (cocaine, methamphetamine) dependency. Method of action: Increases dopamine in the brain by inhibiting dopamine reuptake.

Used to treat nicotine addiction. Method of action: Partial agonist at nicotinic receptors, reducing craving and withdrawal symptoms.

Used for smoking cessation. Method of action: Provides controlled doses of nicotine to ease withdrawal while not containing other harmful chemicals found in tobacco.

Used to treat alcohol and sometimes other addictions. Method of action: Anticonvulsant that enhances GABA activity and suppresses glutamate neurotransmission.

Used to reverse opioid overdose. Method of action: Opioid antagonist that quickly displaces opioids from their receptors, reversing the effects of overdose.

Used to treat alcohol dependence and withdrawal symptoms. Method of action: Modulates GABA neurotransmission, though its precise mechanism in alcohol dependence is not fully understood.

Used to treat alcohol dependence. Method of action: GABA-B receptor agonist, which may reduce cravings and withdrawal symptoms.

Used to treat opioid withdrawal. Method of action: Alpha-2 adrenergic receptor agonist that can reduce sympathetic outflow, leading to reduced withdrawal symptoms.

Used to treat chronic alcoholism. Method of action: Causes unpleasant physical reactions when alcohol is ingested by interfering with alcohol metabolism.

Off-label use for treating alcohol dependence and PTSD-related symptoms. Method of action: Alpha-1 adrenergic receptor antagonist that may help reduce alcohol cravings and nightmares.

Used to treat opioid dependence. Method of action: Buprenorphine is a partial opioid agonist and naloxone is an opioid antagonist, combination reduces risk of misuse.

Used to treat alcohol and opioid dependence. Method of action: Injectable extended-release formulation of naltrexone blocks opioid receptors and reduces craving for alcohol.

Used to treat alcohol dependence and maintain abstinence. Method of action: It stabilizes chemical signaling in the brain that would otherwise be disrupted by alcohol withdrawal.

Used for smoking cessation. Method of action: Acts as a nicotinic receptor partial agonist, thus reducing cravings and withdrawal symptoms of nicotine.