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Primary use: Treatment of anxiety and panic disorders. Contraindications: Severe respiratory insufficiency, sleep apnea, liver impairment.

Primary use: Management of anxiety disorders, alcohol withdrawal symptoms, muscle spasms. Contraindications: Myasthenia gravis, severe respiratory insufficiency, pediatric patients under 6 months.

Primary use: Anxiety relief, preanesthetic medication, status epilepticus. Contraindications: Acute narrow-angle glaucoma, sleep apnea, severe respiratory insufficiency.

Primary use: Prevention and treatment of seizures, panic disorder management. Contraindications: Severe liver disease, acute angle closure glaucoma, history of sensitivity to benzodiazepines.

Primary use: Management of chronic anxiety. Contraindications: Hypersensitivity to buspirone, concurrent use of MAO inhibitors, severe renal or hepatic impairment.

Primary use: Management of situational anxiety and performance anxiety. Contraindications: Asthma, bradycardia, certain heart block conditions.

Primary use: Generalized anxiety disorder and depression treatment. Contraindications: Concurrent use with MAO inhibitors, pregnancy, children under 12 years of age.

Primary use: Treats panic disorder, obsessive-compulsive disorder, PTSD, and social anxiety disorder. Contraindications: Use of MAO inhibitors or pimozide, disulfiram can cause reaction due to alcohol content of the concentrate form.

Primary use: Treatment for generalized anxiety disorder, social anxiety, PTSD, panic disorder. Contraindications: Concurrent use of MAO inhibitors or thioridazine, pregnancy, especially in the first trimester.

Primary use: Generalized anxiety disorder, panic disorder, and social anxiety disorder management. Contraindications: Concurrent use of MAO inhibitors, uncontrolled angle-closure glaucoma.

Primary use: Treatment of panic disorder with or without agoraphobia, OCD, and certain eating disorders. Contraindications: Concurrent use with MAO inhibitors, thioridazine or pimozide, known hypersensitivity to fluoxetine.

Primary use: Symptomatic relief of anxiety and tension. Contraindications: Prolonged QT interval, previous hypersensitivity to hydroxyzine, pregnancy (especially first trimester).

Primary use: Off-label for social anxiety disorder, prescribed primarily for neuropathic pain. Contraindications: Hypersensitivity to gabapentin, caution required with renal impairment.

Primary use: Off-label for generalized anxiety disorder, primarily prescribed for depression Contraindications: Concurrent use with MAO inhibitors, caution with severe renal or hepatic impairment.

Primary use: Treatment of OCD, may help with panic disorder. Contraindications: Concurrent use with MAOI drugs or recent myocardial infarction patients.

Primary use: Treatment of depression and sometimes prescribed for various anxiety disorders. Contraindications: Use with MAO inhibitors or pimozide, QT interval prolongation.

Primary use: Off-label for generalized anxiety disorder, primarily indicated for the treatment of schizophrenia and bipolar disorder. Contraindications: Known hypersensitivity to quetiapine, history of myocardial infarction or untreated heart failure.

Primary use: Generalized anxiety disorder among its various approved uses, including nerve pain. Contraindications: Known hypersensitivity to pregabalin, caution in patients with a history of drug abuse.

Primary use: Off-label for panic disorder, prescribed primarily for major depressive disorder. Contraindications: Recently had a heart attack, use of MAO inhibitors, severe liver disease.

Primary use: Off-label for anxiety, mainly used as an antidepressant and smoking cessation aid. Contraindications: Seizure disorders, bulimia, anorexia nervosa.

Primary use: General anxiety disorder, also used for major depressive disorder and fibromyalgia. Contraindications: MAOI use in the past 14 days, uncontrolled narrow-angle glaucoma, severe renal impairment.

Primary use: Off-label for anxiety, primarily used for major depressive disorder. Contraindications: Use with MAO inhibitors, caution in patients with cardiac disease or priapism history.

Primary use: Management of anxiety disorders, alcohol withdrawal syndrome. Contraindications: Myasthenia gravis, chronic obstructive pulmonary disease (COPD), sleep apnea.

Primary use: Off-label for anxiety, primarily prescribed for short-term treatment of insomnia. Contraindications: Severe respiratory insufficiency, myasthenia gravis, history of complex sleep behaviors like sleep-driving.