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Antidepressants Overview
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Sertraline
Drug class: Selective Serotonin Reuptake Inhibitor (SSRI); Possible side effects: Nausea, Insomnia, Sexual dysfunction
Fluoxetine
Drug class: Selective Serotonin Reuptake Inhibitor (SSRI); Possible side effects: Headache, Nervousness, Sleep disturbances
Citalopram
Drug class: Selective Serotonin Reuptake Inhibitor (SSRI); Possible side effects: Dry mouth, Tremor, Diarrhea
Escitalopram
Drug class: Selective Serotonin Reuptake Inhibitor (SSRI); Possible side effects: Fatigue, Drowsiness, Increased sweating
Paroxetine
Drug class: Selective Serotonin Reuptake Inhibitor (SSRI); Possible side effects: Constipation, Dizziness, Ejaculatory disturbance
Venlafaxine
Drug class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI); Possible side effects: Increased blood pressure, Nausea, Somnolence
Duloxetine
Drug class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI); Possible side effects: Dry mouth, Fatigue, Constipation
Desvenlafaxine
Drug class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI); Possible side effects: Dizziness, Insomnia, Sweating
Bupropion
Drug class: Norepinephrine-Dopamine Reuptake Inhibitor (NDRI); Possible side effects: Weight loss, Insomnia, Tinnitus
Mirtazapine
Drug class: Noradrenergic and Specific Serotonergic Antidepressant (NaSSA); Possible side effects: Increased appetite, Sedation, Weight gain
Trazodone
Drug class: Serotonin Antagonist and Reuptake Inhibitor (SARI); Possible side effects: Sedation, Orthostatic hypotension, Priapism
Nefazodone
Drug class: Serotonin Antagonist and Reuptake Inhibitor (SARI); Possible side effects: Dizziness, Nausea, Liver failure (rare but serious side effect)
Amitriptyline
Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Dry mouth, Blurred vision, Constipation
Nortriptyline
Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Drowsiness, Dizziness, Weight gain
Imipramine
Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Tremor, Erectile dysfunction, Heart palpitations
Clomipramine
Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Seizures, Gastrointestinal upset, Sexual dysfunction
Doxepin
Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Hypotension, Euphoria, Sleep disturbances
Phenelzine
Drug class: Monoamine Oxidase Inhibitor (MAOI); Possible side effects: Hypertensive crisis, Insomnia, Weight gain
Tranylcypromine
Drug class: Monoamine Oxidase Inhibitor (MAOI); Possible side effects: Orthostatic hypotension, Dizziness, Sleep disturbances
Isocarboxazid
Drug class: Monoamine Oxidase Inhibitor (MAOI); Possible side effects: Dry mouth, Dizziness, Gastrointestinal disturbances
Vortioxetine
Drug class: Serotonin Modulator and Stimulator (SMS); Possible side effects: Nausea, Diarrhea, Sexual dysfunction
Vilazodone
Drug class: Serotonin Partial Agonist and Reuptake Inhibitor (SPARI); Possible side effects: Diarrhea, Nausea, Headache
Agomelatine
Drug class: Melatonin Receptor Agonist and Serotonin Antagonist; Possible side effects: Headache, Liver enzyme elevation, Dizziness
Selegiline (Transdermal)
Drug class: Monoamine Oxidase Inhibitor (MAOI); Possible side effects: Local skin reactions, Insomnia, Weight loss
Maprotiline
Drug class: Norepinephrine Reuptake Inhibitor (NRI); Possible side effects: Seizure risk, Drowsiness, Anticholinergic effects
Amoxapine
Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Extrapyramidal symptoms, Anxiety, Anticholinergic effects
Reboxetine
Drug class: Norepinephrine Reuptake Inhibitor (NRI); Possible side effects: Insomnia, Dry mouth, Constipation
Levomilnacipran
Drug class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI); Possible side effects: Hyperhidrosis, Tachycardia, Erectile dysfunction
Milnacipran
Drug class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI); Possible side effects: Nausea, Headache, Palpitations
Tianeptine
Drug class: Serotonin Reuptake Enhancer (SRE); Possible side effects: Nausea, Constipation, Dizziness
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