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Antidepressants Overview

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Sertraline

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Drug class: Selective Serotonin Reuptake Inhibitor (SSRI); Possible side effects: Nausea, Insomnia, Sexual dysfunction

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Fluoxetine

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Drug class: Selective Serotonin Reuptake Inhibitor (SSRI); Possible side effects: Headache, Nervousness, Sleep disturbances

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Citalopram

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Drug class: Selective Serotonin Reuptake Inhibitor (SSRI); Possible side effects: Dry mouth, Tremor, Diarrhea

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Escitalopram

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Drug class: Selective Serotonin Reuptake Inhibitor (SSRI); Possible side effects: Fatigue, Drowsiness, Increased sweating

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Paroxetine

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Drug class: Selective Serotonin Reuptake Inhibitor (SSRI); Possible side effects: Constipation, Dizziness, Ejaculatory disturbance

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Venlafaxine

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Drug class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI); Possible side effects: Increased blood pressure, Nausea, Somnolence

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Duloxetine

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Drug class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI); Possible side effects: Dry mouth, Fatigue, Constipation

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Desvenlafaxine

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Drug class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI); Possible side effects: Dizziness, Insomnia, Sweating

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Bupropion

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Drug class: Norepinephrine-Dopamine Reuptake Inhibitor (NDRI); Possible side effects: Weight loss, Insomnia, Tinnitus

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Mirtazapine

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Drug class: Noradrenergic and Specific Serotonergic Antidepressant (NaSSA); Possible side effects: Increased appetite, Sedation, Weight gain

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Trazodone

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Drug class: Serotonin Antagonist and Reuptake Inhibitor (SARI); Possible side effects: Sedation, Orthostatic hypotension, Priapism

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Nefazodone

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Drug class: Serotonin Antagonist and Reuptake Inhibitor (SARI); Possible side effects: Dizziness, Nausea, Liver failure (rare but serious side effect)

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Amitriptyline

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Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Dry mouth, Blurred vision, Constipation

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Nortriptyline

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Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Drowsiness, Dizziness, Weight gain

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Imipramine

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Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Tremor, Erectile dysfunction, Heart palpitations

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Clomipramine

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Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Seizures, Gastrointestinal upset, Sexual dysfunction

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Doxepin

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Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Hypotension, Euphoria, Sleep disturbances

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Phenelzine

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Drug class: Monoamine Oxidase Inhibitor (MAOI); Possible side effects: Hypertensive crisis, Insomnia, Weight gain

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Tranylcypromine

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Drug class: Monoamine Oxidase Inhibitor (MAOI); Possible side effects: Orthostatic hypotension, Dizziness, Sleep disturbances

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Isocarboxazid

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Drug class: Monoamine Oxidase Inhibitor (MAOI); Possible side effects: Dry mouth, Dizziness, Gastrointestinal disturbances

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Vortioxetine

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Drug class: Serotonin Modulator and Stimulator (SMS); Possible side effects: Nausea, Diarrhea, Sexual dysfunction

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Vilazodone

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Drug class: Serotonin Partial Agonist and Reuptake Inhibitor (SPARI); Possible side effects: Diarrhea, Nausea, Headache

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Agomelatine

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Drug class: Melatonin Receptor Agonist and Serotonin Antagonist; Possible side effects: Headache, Liver enzyme elevation, Dizziness

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Selegiline (Transdermal)

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Drug class: Monoamine Oxidase Inhibitor (MAOI); Possible side effects: Local skin reactions, Insomnia, Weight loss

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Maprotiline

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Drug class: Norepinephrine Reuptake Inhibitor (NRI); Possible side effects: Seizure risk, Drowsiness, Anticholinergic effects

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Amoxapine

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Drug class: Tricyclic Antidepressant (TCA); Possible side effects: Extrapyramidal symptoms, Anxiety, Anticholinergic effects

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Reboxetine

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Drug class: Norepinephrine Reuptake Inhibitor (NRI); Possible side effects: Insomnia, Dry mouth, Constipation

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Levomilnacipran

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Drug class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI); Possible side effects: Hyperhidrosis, Tachycardia, Erectile dysfunction

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Milnacipran

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Drug class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI); Possible side effects: Nausea, Headache, Palpitations

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Tianeptine

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Drug class: Serotonin Reuptake Enhancer (SRE); Possible side effects: Nausea, Constipation, Dizziness

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