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Mechanism of action: Enhances the effect of neurotransmitter GABA. Common uses: Anxiety relief, muscle relaxation, anticonvulsant.

Mechanism of action: Binds to GABA receptor complex and potentiates GABA effects. Common uses: Anxiety, pre-anesthetic, status epilepticus.

Mechanism of action: Modulates GABA receptor complex function. Common uses: Generalized anxiety disorder, panic disorder.

Mechanism of action: Agonist at benzodiazepine site of GABA-A receptors. Common uses: Short-term treatment of insomnia.

Mechanism of action: Partial agonist at serotonin 5-HT1A receptors. Common uses: Generalized anxiety disorder.

Mechanism of action: Increases GABAergic activity. Common uses: Panic disorder, seizure disorders.

Mechanism of action: Potentiates GABA-A action. Common uses: Short-term management of insomnia.

Mechanism of action: Enhances GABA activity at the GABAA receptor. Common uses: Preoperative sedation, procedural sedation.

Mechanism of action: Enhances GABA-mediated synaptic inhibition. Common uses: Insomnia.

Mechanism of action: Competitive antagonist at GABAA receptors. Common uses: Benzodiazepine overdose antidote.

Mechanism of action: Prolongs opening of GABAA chloride channels. Common uses: Sedative, anticonvulsant for epilepsy.

Mechanism of action: Modulates GABAA receptor; increases duration of chloride channel opening. Common uses: Sedative, pre-anesthetic.

Mechanism of action: Potentiates GABA by increasing the duration of chloride channel opening. Common uses: Insomnia, preoperative medication.

Mechanism of action: Antagonizes H1 histamine receptors. Common uses: Anxiolytic, sedative, and antiemetic.

Mechanism of action: Enhances GABAA receptors. Common uses: Anxiety, alcohol withdrawal syndrome.

Mechanism of action: Potentiates the effect of GABA at the GABA-A receptor. Common uses: Anxiety disorders, alcohol withdrawal.

Mechanism of action: Unknown, may involve GABAergic mechanisms. Common uses: Short-term relief of anxiety.

Mechanism of action: Enhances GABA action through binding to the benzodiazepine site on the GABA-A receptor. Common uses: Insomnia.

Mechanism of action: Acts on GABA-BZ receptor complex. Common uses: Short-term treatment of insomnia.

Mechanism of action: Agonist at melatonin receptors in the suprachiasmatic nucleus. Common uses: Sleep disorders, jet lag.

Mechanism of action: Acts on GABA-A receptor complex. Common uses: Insomnia with difficulty falling asleep or maintaining sleep.

Mechanism of action: Selective agonist of melatonin MT1 and MT2 receptors. Common uses: Treatment of insomnia characterized by difficulty with sleep onset.

Mechanism of action: Dual orexin receptor antagonist. Common uses: Insomnia, including difficulties with sleep onset and/or sleep maintenance.

Mechanism of action: Binds to the alpha-2-delta subunit of voltage-gated calcium channels in CNS. Common uses: Neuropathic pain, partial seizures, postherpetic neuralgia.