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Immunodeficiencies
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X-linked Agammaglobulinemia (XLA)
Impacted parts: B lymphocytes; Symptoms: Recurrent bacterial infections, absent or reduced mature B cells and immunoglobulins.
Severe Combined Immunodeficiency (SCID)
Impacted parts: T and B lymphocytes; Symptoms: Severe recurrent infections, failure to thrive, chronic diarrhea.
DiGeorge Syndrome
Impacted part: T lymphocytes (Thymic hypoplasia); Symptoms: Heart defects, cleft palate, low calcium level, immune deficiency.
Common Variable Immunodeficiency (CVID)
Impacted parts: B lymphocytes; Symptoms: Recurrent infections, particularly respiratory and gastrointestinal, autoimmune disorders.
Chronic Granulomatous Disease (CGD)
Impacted parts: Phagocytes - neutrophils and macrophages; Symptoms: Recurrent, severe infections with bacteria and fungi, granuloma formation.
Selective IgA Deficiency
Impacted part: B lymphocytes (specific to IgA production); Symptoms: Asymptomatic, or recurrent sinopulmonary and gastrointestinal infections.
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