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Natural Killer Cells
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Origin and Development of NK Cells
NK cells originate from the bone marrow and are part of the innate immune system. Their development involves a differentiation process from lymphoid progenitor cells.
Mechanisms of NK Cell Killing
NK cells can kill target cells through the release of cytotoxic granules containing perforin and granzymes, or through death receptor-mediated apoptosis.
Receptor Types on NK Cells
NK cells possess a variety of receptors, including activating and inhibitory receptors, which help distinguish between healthy cells and abnormal cells, such as cancer cells or virus-infected cells.
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