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Natural Killer Cells
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Origin and Development of NK Cells
NK cells originate from the bone marrow and are part of the innate immune system. Their development involves a differentiation process from lymphoid progenitor cells.
Receptor Types on NK Cells
NK cells possess a variety of receptors, including activating and inhibitory receptors, which help distinguish between healthy cells and abnormal cells, such as cancer cells or virus-infected cells.
Mechanisms of NK Cell Killing
NK cells can kill target cells through the release of cytotoxic granules containing perforin and granzymes, or through death receptor-mediated apoptosis.
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