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Glycoproteins and Proteoglycans

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Laminin

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Structure: Cross-shaped molecule composed of three different polypeptide chains, alpha, beta, and gamma. Biological Function: A major component of the basal lamina, influencing cell differentiation, adhesion, and movement.

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Glycoprotein Hormones

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Structure: Tertiary or quaternary structures with carbohydrate moieties, like luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH). Biological Function: Regulate a wide variety of biological functions such as growth, reproduction, and metabolism.

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Proteoglycans

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Structure: Core protein with covalently attached glycosaminoglycan (GAG) chains. Biological Function: Contributes to the resilience and elasticity of cartilage and acts as a lubricant in joints.

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Mucins

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Structure: High molecular weight glycoproteins with a protein core and a dense carbohydrate coat. Biological Function: Forms a protective mucus layer on epithelial surfaces in the respiratory, digestive, and urogenital systems.

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Collagen

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Structure: Triple helix composed of three polypeptide chains. Biological Function: Provides structural support in connective tissue, bone, cartilage, and blood vessels.

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Fibronectin

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Structure: High molecular weight glycoprotein that forms a disulfide-linked dimer. Biological Function: Involved in cell adhesion, growth, migration, and differentiation.

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Erythropoietin (EPO)

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Structure: Glycoprotein hormone with a complex 3D structure stabilized by glycosylation. Biological Function: Stimulates red blood cell production in the bone marrow.

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Immunoglobulin G (IgG)

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Structure: Y-shaped protein with two heavy chains and two light chains, with carbohydrate groups attached. Biological Function: Mediates the immune response by recognizing and binding to specific antigens.

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