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Significance: Chronic bacterial infection causing skin lesions and nerve damage. Affected Populations: Areas with poor access to healthcare, like some regions of Africa, Asia, and Latin America. Control Efforts: Early diagnosis and multidrug therapy (MDT).

Significance: Parasitic disease leading to neurological impairment and death if untreated. Affected Populations: Sub-Saharan Africa. Control Efforts: Vector control, screening of at-risk populations, and treatment with specific drugs.

Significance: Parasitic infection causing lymphedema and elephantiasis. Affected Populations: Found in 73 countries in Africa, Asia, the Western Pacific, and parts of the Caribbean and South America. Control Efforts: Mass drug administration to eliminate transmission.

Significance: Bacterial infection causing blindness. Affected Populations: Poor, rural communities in developing countries. Control Efforts: Surgery, antibiotics, facial cleanliness, and environmental improvement.

Significance: Parasitic disease causing skin ulcers and vital organ damage. Affected Populations: Found in parts of Asia, Africa, South and Central America, and southern Europe. Control Efforts: Vector control, case detection, and treatment.

Significance: Viral infection causing severe flu-like illness. Affected Populations: Common in more than 100 countries, especially in tropical areas. Control Efforts: Mosquito control, vaccine development.

Significance: Caused by Trypanosoma cruzi, leads to chronic conditions. Affected Populations: Mostly in Latin America. Control Efforts: Vector control, blood screening.

Significance: Viral infection linked to birth defects and neurological complications. Affected Populations: Outbreaks have occurred in Africa, the Americas, Asia, and the Pacific. Control Efforts: Mosquito control, prevention of mosquito bites, and risk communication.

Significance: Chronic debilitating skin and soft tissue infection. Affected Populations: Predominantly affects communities near slow-flowing water in tropical and subtropical regions. Control Efforts: Early detection and combination antibiotic therapy.

Significance: Chronic, progressive bacterial or fungal skin infection. Affected Populations: Agricultural workers in tropical and subtropical areas. Control Efforts: Surgical procedures and long-term antifungal or antibiotic therapy.

Significance: Parasitic disease leading to skin disease and blindness. Affected Populations: Sub-Saharan Africa, Yemen, and parts of Central and South America. Control Efforts: Mass drug administration and vector control efforts.

Significance: Chronic bacterial infection affecting skin, bone, and cartilage. Affected Populations: Children in tropical regions of Africa, Asia, Latin America. Control Efforts: Mass treatment with azithromycin or penicillin.

Significance: Viral disease causing debilitating joint pain and fever. Affected Populations: Numerous outbreaks in Africa, Asia, Europe, and the Americas. Control Efforts: Vector control and avoiding mosquito bites are the primary prevention strategies.

Significance: Parasitic infection leading to painful skin lesions and ulcers. Affected Populations: Remote rural areas in Africa. Control Efforts: Providing safe drinking water, surveillance, and health education.

Significance: Acute diarrheal disease caused by Vibrio cholerae. Affected Populations: Common in regions with inadequate access to clean water and sanitation. Control Efforts: Safe water, sanitation, oral cholera vaccines, and rapid treatment.

Significance: Intestinal worm infections causing nutritional impairment. Affected Populations: Over 1.5 billion people, particularly children in tropical and subtropical climates. Control Efforts: Preventive chemotherapy, health education, and improved sanitation.

Significance: Non-infectious disease causing lymphedema of the lower legs. Affected Populations: Primarily affects individuals in tropical Africa, Central America, and northwest India who walk barefoot on volcanic soil. Control Efforts: Foot hygiene, protective footwear, and compression therapy.

Significance: Tissue infection after ingestion of eggs of the pork tapeworm. Affected Populations: Individuals in areas with poor sanitation and where pigs can contact human feces. Control Efforts: Improved sanitation, education on food safety, and treatment of human tapeworm carriers.

Significance: Caused by parasitic worms, leads to organ damage. Affected Populations: Tropical and subtropical regions, especially in poor communities. Control Efforts: Snail control, mass drug administration, sanitation improvement.