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Prostate cancer is the most common cancer in American men, except for skin cancers. The American Cancer Society's estimates for prostate cancer in the United States for 2021 are about 248,530 new cases and 34,130 deaths from prostate cancer.

About 1 in 8 U.S. women will develop invasive breast cancer over the course of her lifetime. In 2021, an estimated 281,550 new cases of invasive breast cancer were expected to be diagnosed in the U.S., along with 49,290 new cases of non-invasive (in situ) breast cancer.

For 2021, the estimated new cases of Non-Hodgkin lymphoma in the United States were about 81,560 and deaths were approximately 20,720. This type of lymphoma can occur at any age and is often marked by larger than normal lymph nodes, fever, and weight loss.

Lung cancer is the leading cause of cancer death among both men and women; about 1 out of 4 cancer deaths are from lung cancer. Each year, more people die of lung cancer than of colon, breast, and prostate cancers combined.

The American Cancer Society's estimates for melanoma in the United States for 2021 are about 106,110 new melanomas will be diagnosed (about 62,260 in men and 43,850 in women). The estimated deaths from melanoma in the United States for 2021 are about 7,180.

The American Cancer Society's estimates for pancreatic cancer in the United States for 2021 are about 60,430 new cases and 48,220 deaths. Pancreatic cancer accounts for about 3% of all cancers in the US and about 7% of all cancer deaths.

In 2021, there were an estimated 61,090 new cases of leukemia and an estimated 23,660 deaths from leukemia in the United States. There are several types of leukemia, some affecting children and others primarily affecting adults.

In 2021, the American Cancer Society estimated that there would be 149,500 new cases of colorectal cancer and 52,980 deaths from this disease in the United States. Colorectal cancer is the third most common cancer diagnosed in both men and women in the U.S.

The American Cancer Society's estimates for bladder cancer in the United States for 2021 are about 83,730 new cases and 17,200 deaths. Bladder cancer is the fourth most common cancer in men, but it is less common in women.

The American Cancer Society's estimates for endometrial cancer in the United States for 2021 are about 66,570 new cases and 12,940 deaths. Endometrial cancer occurs in the lining of the uterus and is most commonly diagnosed in women aged 55 and older.

For 2021, the American Cancer Society estimated that there would be about 21,410 new cases of ovarian cancer and 13,770 deaths from this cancer in the U.S. The risk of ovarian cancer increases with age and is most common in women ages 50 to 60.

Gallbladder cancer is relatively uncommon in the United States, with an estimated 12,480 new cases in 2021 and about 4,130 deaths. It is more common in women and Native Americans.

There were about 14,480 new cases of cervical cancer diagnosed and 4,290 deaths from the disease in the United States during 2021. Human papillomavirus (HPV) is a major cause of cervical cancer.

The American Cancer Society's estimates for thyroid cancer in the United States for 2021 are about 44,280 new cases (12,150 in men and 32,130 in women). Deaths from thyroid cancer are relatively rare, about 2,200 in 2021.

Liver cancer incidence rates are increasing. In the United States, about 42,230 new cases and 30,230 liver cancer deaths are expected in 2021. Chronic infections with hepatitis B or C are among the most common risk factors.

In 2021, about 76,080 new cases of kidney cancer were expected to be diagnosed in the United States and around 13,780 people were expected to die from this disease. Kidney cancer is one of the 10 most common cancers in both men and women.

It is estimated that in 2021, about 19,260 new esophageal cancer cases were diagnosed in the U.S., and there were approximately 15,530 deaths from this disease. Esophageal cancer is more common in men than in women.

In the United States for 2021, it was estimated that there would be about 26,560 new cases of stomach (gastric) cancer and about 11,180 deaths caused by this disease. Incidence rates are nearly twice as high in men as in women.

In 2021, an estimated 24,530 new cases of brain and other nervous system cancers were to be diagnosed, with about 18,600 deaths expected. Brain cancer incidence rates increase with age, with the highest rates in those aged 75 and older.

The American Cancer Society estimated that in 2021, about 9,470 new cases of testicular cancer would be diagnosed and about 440 men would die from this disease in the United States. Testicular cancer is relatively rare.

Squamous cell carcinoma (SCC) is the second most common form of skin cancer. More than 1 million cases of SCC are diagnosed each year in the U.S., and deaths from SCC are also significant though not high in relation to incidence.

For 2021, about 8,830 new cases of Hodgkin lymphoma were expected to be diagnosed in the U.S. and approximately 960 deaths. The disease is most common among people aged 20-34 and those over 55.

Mesothelioma is a rare cancer associated with asbestos exposure. For 2021, the American Cancer Society estimated about 3,000 new cases of mesothelioma in the U.S. and about 2,500 deaths. The incidence rate has been declining slowly.

In 2021, an estimated 13,130 new cases of soft tissue sarcomas were diagnosed in the United States, with about 5,350 deaths from this cancer. Sarcomas are rare tumors that can grow in connective tissue, including fat, muscle, nerves, and blood vessels.

The American Cancer Society's estimates for multiple myeloma in the United States for 2021 are about 34,920 new cases and 12,410 deaths. This type of cancer affects plasma cells in the bone marrow and is slightly more common in men.

Uterine sarcoma is a rare type of uterine cancer that forms in the muscle and supporting tissues of the uterus. In the United States for 2021, about 2,320 new cases of uterine sarcoma were expected to be diagnosed.

Thymoma and thymic carcinoma are rare thymus cancers, with thymoma being the more common of the two. In the U.S, the estimated number of new cases is not precisely known due to its rareness, but it is believed to be fewer than 1 per 100,000 people annually.

Childhood leukemia is the most common type of cancer in children and teens, accounting for almost 1 out of 3 cancers. In 2021, approximately 3,780 new cases of childhood leukemia were diagnosed in the U.S.

Basal cell carcinoma (BCC) is the most common form of skin cancer. Exact numbers are hard to determine because it is not required to be reported, but it is estimated that over 4 million cases are diagnosed in the U.S. each year.