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Radiation Therapy Basics

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Radiation Oncologist

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A medical doctor specialized in the use of radiation for the treatment of cancer, responsible for determining and prescribing the appropriate course of treatment.

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Linear Accelerator (LINAC)

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A type of equipment that uses high-energy x-rays to treat cancer by delivering radiation beams to the tumor site, sparing normal tissue.

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External Beam Radiation Therapy (EBRT)

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A method of delivering radiation from outside the body, using a linear accelerator to target tumors with high-energy beams.

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Image-Guided Radiation Therapy (IGRT)

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Radiation therapy that uses imaging techniques such as CT, MRI, or X-rays during treatment to improve the precision and accuracy of treatment delivery.

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Stereotactic Body Radiotherapy (SBRT)

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A highly precise and intense form of radiation therapy that targets tumors in the body with high doses of radiation, while minimizing the dose to surrounding healthy tissues.

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Isodose Curves

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Contours that represent the distribution of a prescribed radiation dose within the treatment area, used to visualize and optimize the dose delivered to the tumor and surrounding tissues.

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Dose (Radiation Dose)

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The amount of radiation energy absorbed by the body's tissues, measured in Grays (Gy), a fundamental aspect of planning and delivering radiation therapy.

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Proton Therapy

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A type of radiation therapy that uses protons rather than X-rays to treat cancer, allowing for more precise targeting of radiation doses with less impact on surrounding healthy tissue.

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Acute Radiation Syndrome (ARS)

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A serious illness that occurs when the entire body (or most of it) receives a high dose of radiation, usually over a short period of time, with symptoms depending on the exposure level.

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Radiation Therapist

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A healthcare professional trained to administer the prescribed radiation treatment plans and operate radiation therapy equipment.

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Intensity-Modulated Radiation Therapy (IMRT)

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An advanced mode of high-precision radiation therapy that uses computer-controlled linear accelerators to deliver precise radiation doses to a malignant tumor or specific areas within the tumor.

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Radiobiology

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The study of the interactions between ionizing radiation and living cells, critical for understanding the effects of radiation and improving radiation therapy treatments.

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Fractionation

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A treatment schedule in radiation therapy where the total dose of radiation is divided into smaller doses and treatments are given over a period of time.

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Conformal Radiation Therapy

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A radiation treatment technique that shapes the radiation beams to closely approximate the shape of the tumor, thereby protecting nearby healthy tissues from radiation.

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Radiation Dosimetrist

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A professional who specializes in radiation treatment planning, calculating the dose distributions and machine settings to deliver the prescribed dose to the patient.

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Radiosensitivity

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Refers to the susceptibility of cancer cells or normal tissues to the damaging effects of radiation, influencing how they respond to radiation therapy.

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4 Rs of Radiobiology

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The four key mechanisms that contribute to the effectiveness of fractionated radiation therapy: Repair, Redistribution, Reoxygenation, and Repopulation.

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Brachytherapy

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A form of internal radiation therapy where radioactive material is placed directly into or near a tumor, providing a high dose with minimal exposure to surrounding healthy tissues.

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Total Body Irradiation (TBI)

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A form of radiation therapy where the entire body is exposed to radiation, often used as part of the conditioning regimen for bone marrow or stem cell transplantation.

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Radiation Toxicity

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Refers to the side effects or complications that arise from radiation therapy, affecting both the cancer cells as well as potentially the normal tissues.

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Three-Dimensional Conformal Radiation Therapy (3D-CRT)

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A radiation therapy technique that uses computerized imaging to create a 3D representation of the tumor, allowing for more accurate delivery of radiation to the cancerous area while sparing healthy tissue.

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Simulation

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Prior to actual radiation treatment, a process where imaging studies are used to plan the precise location and dose of radiation that will be delivered.

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Radiotherapy Treatment Planning

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The process of determining the radiation doses, methods, and techniques to be used for patient treatment, ensuring maximum tumor control with minimum harm to healthy tissue.

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Tumor Volume

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A measure that defines the three-dimensional space occupied by the tumor, which is essential for accurate dosage calculation and efficient radiation therapy planning.

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Bolus

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A tissue-equivalent material placed on the skin surface to ensure adequate dose delivery at the skin level or to superficial tumors during radiation therapy.

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