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Cytoskeletal Elements

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Nuclear Lamina

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Function: Provides structural support to the nuclear envelope, participates in DNA replication and cell division, and regulates gene expression. Location: Lies directly beneath the inner nuclear membrane.

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Kinesins and Dyneins

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Function: Motor proteins that move along microtubules in an ATP-dependent manner, transporting vesicles, organelles, and other cellular components. Location: Distributed throughout the cell along microtubule tracks.

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Actin Filaments (Microfilaments)

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Function: Involved in cell motility, structure, and integrity; provide mechanical support for the cell; essential for muscle contraction, cell division, and cytokinesis. Location: Found beneath the plasma membrane and throughout the cell cortex.

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Centrioles

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Function: Serve as the main organizing centers for microtubules and are key during cell division for the formation of the spindle apparatus. Location: Usually found near the nucleus, within a region known as the centrosome.

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Cilia and Flagella

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Function: Provide mobility to cells or move substances over the cell surface. Composed of a '9+2' arrangement of microtubules. Location: Extending from the cell surface.

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Microtubules

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Function: Provide structural support and shape to cells, aid in cell division, and serve as tracks for the movement of organelles. Location: Throughout the cell, radiating from the centrosome.

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Intermediate Filaments

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Function: Provide mechanical strength to cells, maintain cell integrity, and resist stress. Participate in cell adhesion. Location: Found throughout the cell but particularly concentrated at cell-cell junctions.

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Lamins

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Function: Provide a scaffold for the nuclear envelope and help organize the nuclear contents. Involved in DNA replication and cell division. Location: Lining the inner membrane of the nuclear envelope.

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Spectrin

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Function: Maintains cell shape and helps to organize the arrangement of other cytoskeletal proteins. Critical for the elasticity of the red blood cell membrane. Location: Associated with the cytoplasmic side of the plasma membrane.

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Desmin

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Function: Connects sarcomeres in muscle cells and maintains the alignment and structural integrity of muscle fibers. Location: Primarily found in muscle cells interconnecting adjacent sarcomeres.

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