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The Central Dogma of Biology
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RNA Processing
The modifications of RNA after transcription, including splicing, 5' capping, and polyadenylation, which lead to a mature form of mRNA that's ready for translation.
Protein Folding
The physical process by which a polypeptide folds into its characteristic and functional three-dimensional structure from a random coil after translation.
Translation
The process where ribosomes synthesize proteins using the mature mRNA transcript as a template. tRNAs bring amino acids to the ribosome corresponding to the three-nucleotide codons of the mRNA.
DNA Replication
The process by which a DNA molecule is copied to produce two identical DNA molecules. It is essential for cell division and is the basis for biological inheritance.
Transcription
The synthesis of RNA from a DNA template where the code in the DNA is converted into a complementary RNA code. Transcription is the first step of gene expression.
RNA Splicing
A process occurring after transcription in which introns are removed and exons are joined to create a contiguous coding sequence in the mRNA.
DNA Repair
A collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome to prevent mutations.
Post-translational Modification
Chemical changes to the protein that may be critical to its final function, such as phosphorylation, methylation, acetylation, ubiquitination, and glycosylation.
Non-coding RNA Function
Refers to the role of RNA molecules not translated into protein but have roles in gene regulation, RNA processing, and other cellular processes, like tRNA and rRNA.
Gene Expression Regulation
The control of the amount and timing of appearance of the functional product of a gene which enables the cells to produce the protein only when needed.
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