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The Central Dogma of Biology

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RNA Processing

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The modifications of RNA after transcription, including splicing, 5' capping, and polyadenylation, which lead to a mature form of mRNA that's ready for translation.

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Protein Folding

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The physical process by which a polypeptide folds into its characteristic and functional three-dimensional structure from a random coil after translation.

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Translation

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The process where ribosomes synthesize proteins using the mature mRNA transcript as a template. tRNAs bring amino acids to the ribosome corresponding to the three-nucleotide codons of the mRNA.

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DNA Replication

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The process by which a DNA molecule is copied to produce two identical DNA molecules. It is essential for cell division and is the basis for biological inheritance.

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Transcription

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The synthesis of RNA from a DNA template where the code in the DNA is converted into a complementary RNA code. Transcription is the first step of gene expression.

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RNA Splicing

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A process occurring after transcription in which introns are removed and exons are joined to create a contiguous coding sequence in the mRNA.

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DNA Repair

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A collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome to prevent mutations.

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Post-translational Modification

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Chemical changes to the protein that may be critical to its final function, such as phosphorylation, methylation, acetylation, ubiquitination, and glycosylation.

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Non-coding RNA Function

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Refers to the role of RNA molecules not translated into protein but have roles in gene regulation, RNA processing, and other cellular processes, like tRNA and rRNA.

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Gene Expression Regulation

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The control of the amount and timing of appearance of the functional product of a gene which enables the cells to produce the protein only when needed.

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