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Vitamins and Coenzymes
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Vitamin B1
Thiamine Pyrophosphate(TPP); act as a coenzyme in the decarboxylation of alpha-keto acids, such as in the conversion of pyruvate to acetyl-CoA.
Vitamin B2
Flavin adenine dinucleotide (FAD) and Flavin mononucleotide (FMN); these are redox coenzymes involved in several reactions in the electron transport chain and the citric acid cycle.
Vitamin B3
Nicotinamide adenine dinucleotide (NAD+) and Nicotinamide adenine dinucleotide phosphate (NADP+); involved in redox reactions, carrying electrons from one reaction to another.
Vitamin B5
Coenzyme A (CoA); vital for the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle.
Vitamin B6
Pyridoxal phosphate (PLP); a coenzyme in various enzymatic reactions within amino acid metabolism, including transamination, deamination, and decarboxylation.
Vitamin B7
Biotin; serves as a coenzyme in carboxylation reactions, adding a carboxyl group (COOH) to substrates, important for gluconeogenesis and fatty acid synthesis.
Vitamin B9
Tetrahydrofolate (THF); acts as a carrier of methyl, formyl, and methenyl groups in the synthesis of nucleotides and amino acids.
Vitamin B12
5'-Deoxyadenosylcobalamin and Methylcobalamin; they are cofactors involved in the metabolism of fatty acids and amino acids. Specifically, involved in DNA synthesis and regulation as well as fatty acid, amino acid metabolism.
Vitamin C
Ascorbic Acid; involved as a cofactor in the synthesis of collagen, the conversion of dopamine to noradrenaline and as an antioxidant.
Vitamin A
Retinal; acts as a coenzyme in the visual cycle, which is vital for healthy vision, and Retinoic Acid; critical for gene transcription.
Vitamin D
1,25-dihydroxycholecalciferol (Calcitriol); acts as a hormone to regulate calcium and phosphate metabolism, which are crucial for maintaining healthy bones and teeth.
Vitamin E
Tocopherols and Tocotrienols; act as antioxidants to protect cell membranes from oxidative damage.
Vitamin K
Phylloquinone and Menaquinones; are cofactors for the carboxylation of specific glutamate residues in proteins to form gamma-carboxyglutamic acid, which is essential for clotting factor function.
Pantothenic Acid
Coenzyme A (CoA); as stated with Vitamin B5, it’s pivotal for the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle.
Biotin
Biotin; (repeated from Vitamin B7) acts as a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.
Niacin
Nicotinamide adenine dinucleotide (NAD) and Nicotinamide adenine dinucleotide phosphate (NADP); (repeated from Vitamin B3) serve in oxidation and reduction reactions that convert energy from food into cellular usable forms.
Folic Acid
Tetrahydrofolate (THF); (repeated from Vitamin B9) functions in transferring single-carbon units in the synthesis of nucleic acids and metabolism of amino acids.
Cobalamin
Cobalamin coenzymes (5'-Deoxyadenosylcobalamin and Methylcobalamin); (repeated from Vitamin B12) required for the synthesis of methionine, the metabolism of fatty acids and energy production.
Riboflavin
Flavin adenine dinucleotide (FAD) and Flavin mononucleotide (FMN); (repeated from Vitamin B2) they are components of complex II of the electron transport chain in mitochondria.
Pyridoxine
Pyridoxal phosphate (PLP); (repeated from Vitamin B6) it's the active form that acts on glycogen phosphorylase activity, and aids in the conversion of glycogen to glucose-1-phosphate.
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